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Principal Investigators

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Chan, Danny

  • Role of cellular stress signals in the pathogenesis of osteochondrodysplasias
  • Extracellular matrix in stem cell maintenance and differentiation
  • Generation and analysis of mouse models with skeletal abnormal abnormalities or intervertebral disc degeneration
  • Molecular mechanisms for skeletal patterning: Joint formation and digit patterning

Chang, Raymond Chuen Chung

  • Alzheimer's disease
  • Neurodegeneration
  • Glaucoma
  • Parkinson's disease
  • Chinese medicine

Huen, Michael Shing Yan

  • DNA Damage Detection and Repair Control

Jin, Dong-Yan

  • Molecular virology and oncology

Li, David Xiang (Joint Appointment with Department of Chemistry)

  • Chemical proteomics and epigenetics
  • Regulation and function of histone modifications
  • Chemical biology approaches to identify epigenetic ‘readers’, ‘erasers’ and ‘writers’
  • Protein target identification of small molecules (i.e., drug target I.D.) and mapping drug binding sites.

Liu, Pengtao

  • Establishment, characterization and application of totipotent and pluripotent stem cells
  • Hematopoiesis and immune cell functions
  • Cancer cell killers and immunotherapies

Ma, Stephanie Kwai Yee

  • Exploiting stemness as a cancer cell vulnerability

Tanner, Julian Alexander

  • Chemical Biology
  • Directed Nucleic Acid Evolution for Biomedical Application
  • Inorganic Polyphosphate Function
  • Transdisciplinarity

Wong, Jason Wing Hon

  • Cancer Genomics
  • Mutational processes
  • Gene regulation
  • Bioinformatics and computational biology

Zhou, Zhongjun

  • Aging, Chromatin Dynamics and Genomic maintenance
  • Stem cell self-renewal and differentiation in development, aging and cancer
  • Extracellular matrix and cell surface proteinases in regulation of growth factor signalling in development and diseases