CDON suppresses apoptosis in phalangeal joint cavitation in the pathogenesis of Brachydactyly type A1

Adrian On Wah Leung^1,2*, Andrew Chung Hin Poon^1*, Xue Wang^1*, Chen Feng^1,2, Peikai Chen^1,3, Zhengfan Zheng¹, Michael Kai-Tsun To^3,4, Wilson Cheuk Wing Chan^1,3, Martin Cheung¹, and Danny Chan¹

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10x digits only: MPW145/MPB145 (n=12,240 cells)

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MPW145: Wildtype mouse digit MP-III at E14.5
MPB145: BDA1 mouse digit MP-III at E14.5

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¹ School of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China;
² Hebei Orthopedic Clinical Research Center, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, Hebei, China;
³ Department of Orthopaedics Surgery and Traumatology, The University of Hong Kong -Shenzhen Hospital (HKU-SZH), Shenzhen, China;
⁴ Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong, China

^* These authors contributed equally to this manuscript




Correspondence should be addressed to:
Danny Chan
School of Biomedical Sciences
Faculty of Medicine
The University of Hong Kong
21 Sassoon Road, Hong Kong
Email: chand@hku.hk
Tel.: +852 3917 9482