TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols R-MMU-75955 RNA Polymerase II Transcription Elongation 0.00113512471594234 -6.78101275219782 56 2 0.25 8 8608 12455,235497 Ccnt1,Leo1 R-MMU-112382 Formation of RNA Pol II elongation complex 0.00113512471594234 -6.78101275219782 56 2 0.25 8 8608 12455,235497 Ccnt1,Leo1 R-MMU-674695 RNA Polymerase II Pre-transcription Events 0.00213574525669864 -6.14893962684165 77 2 0.25 8 8608 12455,235497 Ccnt1,Leo1 R-MMU-5660668 CLEC7A/inflammasome pathway 0.00371293914376145 -5.59593149396691 4 1 0.125 8 8608 12370 Casp8 R-MMU-75157 FasL/ CD95L signaling 0.00371293914376145 -5.59593149396691 4 1 0.125 8 8608 12370 Casp8 R-MMU-75158 TRAIL signaling 0.00463928694556153 -5.3731946000788 5 1 0.125 8 8608 12370 Casp8 R-MMU-73857 RNA Polymerase II Transcription 0.00699248519098871 -4.96291925073256 141 2 0.25 8 8608 12455,235497 Ccnt1,Leo1 R-MMU-75108 Activation, myristolyation of BID and translocation to mitochondria 0.00925973034863104 -4.68208035076629 10 1 0.125 8 8608 12370 Casp8 R-MMU-3371378 Regulation by c-FLIP 0.00925973034863104 -4.68208035076629 10 1 0.125 8 8608 12370 Casp8 R-MMU-140534 Ligand-dependent caspase activation 0.00925973034863104 -4.68208035076629 10 1 0.125 8 8608 12370 Casp8 R-MMU-69416 Dimerization of procaspase-8 0.00925973034863104 -4.68208035076629 10 1 0.125 8 8608 12370 Casp8 R-MMU-5218900 CASP8 activity is inhibited 0.00925973034863104 -4.68208035076629 10 1 0.125 8 8608 12370 Casp8 R-MMU-264870 Caspase-mediated cleavage of cytoskeletal proteins 0.0111026462282409 -4.50057180013574 12 1 0.125 8 8608 12370 Casp8 R-MMU-5675482 Regulation of necroptotic cell death 0.0111026462282409 -4.50057180013574 12 1 0.125 8 8608 12370 Casp8 R-MMU-1475029 Reversible hydration of carbon dioxide 0.0111026462282409 -4.50057180013574 12 1 0.125 8 8608 12349 Car2 R-MMU-1247673 Erythrocytes take up oxygen and release carbon dioxide 0.0120229788046559 -4.4209355598907 13 1 0.125 8 8608 12349 Car2 R-MMU-5218859 Regulated Necrosis 0.0129425618378044 -4.34723403131248 14 1 0.125 8 8608 12370 Casp8 R-MMU-5213460 RIPK1-mediated regulated necrosis 0.0129425618378044 -4.34723403131248 14 1 0.125 8 8608 12370 Casp8 R-MMU-162710 Synthesis of glycosylphosphatidylinositol (GPI) 0.0147794813660007 -4.21451545433481 16 1 0.125 8 8608 55981 Pigb R-MMU-1237044 Erythrocytes take up carbon dioxide and release oxygen 0.0156968189069923 -4.15429720454658 17 1 0.125 8 8608 12349 Car2 R-MMU-1480926 O2/CO2 exchange in erythrocytes 0.0156968189069923 -4.15429720454658 17 1 0.125 8 8608 12349 Car2 R-MMU-5357769 Caspase activation via extrinsic apoptotic signalling pathway 0.0184443489028342 -3.99299724794205 20 1 0.125 8 8608 12370 Casp8 R-MMU-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 0.0220972822415369 -3.81230065351661 24 1 0.125 8 8608 12455 Ccnt1 R-MMU-168638 NOD1/2 Signaling Pathway 0.0230086547655703 -3.77188483967865 25 1 0.125 8 8608 12370 Casp8 R-MMU-5357905 Regulation of TNFR1 signaling 0.0248291704796722 -3.69573608800755 27 1 0.125 8 8608 12370 Casp8 R-MMU-8866654 E3 ubiquitin ligases ubiquitinate target proteins 0.0266467172136017 -3.62508931743611 29 1 0.125 8 8608 235497 Leo1 R-MMU-111465 Apoptotic cleavage of cellular proteins 0.0311776219870999 -3.46805468551245 34 1 0.125 8 8608 12370 Casp8 R-MMU-109606 Intrinsic Pathway for Apoptosis 0.0338872972917878 -3.3847150459742 37 1 0.125 8 8608 12370 Casp8 R-MMU-75893 TNF signaling 0.0338872972917878 -3.3847150459742 37 1 0.125 8 8608 12370 Casp8 R-MMU-201722 Formation of the beta-catenin:TCF transactivating complex 0.0347890475690232 -3.35845266676609 38 1 0.125 8 8608 235497 Leo1 R-MMU-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer 0.0356900612928825 -3.33288302411302 39 1 0.125 8 8608 12455 Ccnt1 R-MMU-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 0.0374898811481186 -3.28368421846824 41 1 0.125 8 8608 12370 Casp8 R-MMU-73887 Death Receptor Signalling 0.0383886883099019 -3.25999243804724 42 1 0.125 8 8608 12370 Casp8 R-MMU-6796648 TP53 Regulates Transcription of DNA Repair Genes 0.0392867609790683 -3.23686768762224 43 1 0.125 8 8608 12455 Ccnt1 R-MMU-75153 Apoptotic execution phase 0.0392867609790683 -3.23686768762224 43 1 0.125 8 8608 12370 Casp8 R-MMU-8852135 Protein ubiquitination 0.0455527471069552 -3.08888434739209 50 1 0.125 8 8608 235497 Leo1 R-MMU-170834 Signaling by TGF-beta Receptor Complex 0.0553270561908314 -2.89449322806314 61 1 0.125 8 8608 12455 Ccnt1 R-MMU-3214858 RMTs methylate histone arginines 0.0623805235195784 -2.77450217541098 69 1 0.125 8 8608 15469 Prmt1 R-MMU-6807505 RNA polymerase II transcribes snRNA genes 0.0632589584430134 -2.7605185259412 70 1 0.125 8 8608 12455 Ccnt1 R-MMU-163125 Post-translational modification: synthesis of GPI-anchored proteins 0.0789481226629267 -2.53896431737351 88 1 0.125 8 8608 55981 Pigb R-MMU-5607764 CLEC7A (Dectin-1) signaling 0.0841264978713869 -2.47543368586952 94 1 0.125 8 8608 12370 Casp8 R-MMU-109581 Apoptosis 0.0858469525625385 -2.45518918950179 96 1 0.125 8 8608 12370 Casp8 R-MMU-5357801 Programmed Cell Death 0.0884223323520446 -2.42563071282693 99 1 0.125 8 8608 12370 Casp8 R-MMU-5621481 C-type lectin receptors (CLRs) 0.103741714587208 -2.26585098246066 117 1 0.125 8 8608 12370 Casp8 R-MMU-114608 Platelet degranulation 0.118835355227452 -2.13001631340388 135 1 0.125 8 8608 21346 Tagln2 R-MMU-76005 Response to elevated platelet cytosolic Ca2+ 0.122988356761508 -2.09566558856585 140 1 0.125 8 8608 21346 Tagln2 R-MMU-201681 TCF dependent signaling in response to WNT 0.146739734963962 -1.91909477185873 169 1 0.125 8 8608 235497 Leo1 R-MMU-3247509 Chromatin modifying enzymes 0.162790249563747 -1.81529271932188 189 1 0.125 8 8608 15469 Prmt1 R-MMU-4839726 Chromatin organization 0.162790249563747 -1.81529271932188 189 1 0.125 8 8608 15469 Prmt1 R-MMU-597592 Post-translational protein modification 0.173189334353923 -1.75336986469264 821 2 0.25 8 8608 55981,235497 Pigb,Leo1 R-MMU-195721 Signaling by Wnt 0.200238212479878 -1.60824755878681 237 1 0.125 8 8608 235497 Leo1 R-MMU-76002 Platelet activation, signaling and aggregation 0.217656582578276 -1.5248367675713 260 1 0.125 8 8608 21346 Tagln2 R-MMU-3700989 Transcriptional Regulation by TP53 0.219903887272508 -1.51456470412197 263 1 0.125 8 8608 12455 Ccnt1 R-MMU-392499 Metabolism of proteins 0.271349693137769 -1.30434690934578 1097 2 0.25 8 8608 55981,235497 Pigb,Leo1 R-MMU-74160 Gene Expression 0.288961399083587 -1.24146216697541 1145 2 0.25 8 8608 12455,235497 Ccnt1,Leo1 R-MMU-168249 Innate Immune System 0.300737474742797 -1.20151757173509 1177 2 0.25 8 8608 12370,223978 Casp8,Cpped1 R-MMU-212436 Generic Transcription Pathway 0.316032800828887 -1.15190927069067 399 1 0.125 8 8608 12455 Ccnt1 R-MMU-109582 Hemostasis 0.389664955513231 -0.942467997514003 515 1 0.125 8 8608 21346 Tagln2 R-MMU-162582 Signal Transduction 0.412602100033179 -0.885271588602294 2462 3 0.375 8 8608 12370,12455,235497 Casp8,Ccnt1,Leo1 R-MMU-6798695 Neutrophil degranulation 0.414559512431341 -0.880538738280227 557 1 0.125 8 8608 223978 Cpped1 R-MMU-168256 Immune System 0.481783086148607 -0.730261294962189 1678 2 0.25 8 8608 12370,223978 Casp8,Cpped1 R-MMU-1430728 Metabolism 0.854091557570627 -0.157716880670123 1840 1 0.125 8 8608 12349 Car2 R-MMU-432040 Vasopressin regulates renal water homeostasis via Aquaporins 0.999999999972792 -2.72075600768709e-11 42 0 0 8 8608 R-MMU-1236974 ER-Phagosome pathway 0.999999999972792 -2.72075600768709e-11 42 0 0 8 8608 R-MMU-5693579 Homologous DNA Pairing and Strand Exchange 0.999999999972792 -2.72075600768709e-11 42 0 0 8 8608 R-MMU-917937 Iron uptake and transport 0.999999999972792 -2.72075600768709e-11 42 0 0 8 8608 R-MMU-166166 MyD88-independent TLR3/TLR4 cascade 0.999999999978442 -2.15574992607884e-11 76 0 0 8 8608 R-MMU-73854 RNA Polymerase I Promoter Clearance 0.999999999978442 -2.15574992607884e-11 76 0 0 8 8608 R-MMU-2559580 Oxidative Stress Induced Senescence 0.999999999978442 -2.15574992607884e-11 76 0 0 8 8608 R-MMU-5334118 DNA methylation 0.999999999978442 -2.15574992607884e-11 76 0 0 8 8608 R-MMU-168164 Toll Like Receptor 3 (TLR3) Cascade 0.999999999978442 -2.15574992607884e-11 76 0 0 8 8608 R-MMU-176408 Regulation of APC/C activators between G1/S and early anaphase 0.999999999978442 -2.15574992607884e-11 76 0 0 8 8608 R-MMU-69275 G2/M Transition 0.999999999981157 -1.88425426199387e-11 164 0 0 8 8608 R-MMU-211897 Cytochrome P450 - arranged by substrate type 0.99999999998157 -1.84300836760216e-11 99 0 0 8 8608 R-MMU-163685 Integration of energy metabolism 0.99999999998157 -1.84300836760216e-11 99 0 0 8 8608 R-MMU-196854 Metabolism of vitamins and cofactors 0.999999999981946 -1.80539348360416e-11 161 0 0 8 8608 R-MMU-168898 Toll-Like Receptors Cascades 0.999999999982155 -1.78450134431272e-11 132 0 0 8 8608 R-MMU-15869 Metabolism of nucleotides 0.999999999984602 -1.5397898794372e-11 95 0 0 8 8608 R-MMU-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 0.999999999984602 -1.5397898794372e-11 95 0 0 8 8608 R-MMU-2672351 Stimuli-sensing channels 0.999999999984602 -1.5397898794372e-11 95 0 0 8 8608 R-MMU-4420097 VEGFA-VEGFR2 Pathway 0.999999999985582 -1.44181087534037e-11 287 0 0 8 8608 R-MMU-5218921 VEGFR2 mediated cell proliferation 0.999999999986997 -1.30026436168555e-11 222 0 0 8 8608 R-MMU-69481 G2/M Checkpoints 0.999999999987246 -1.27541315602366e-11 147 0 0 8 8608 R-MMU-5632684 Hedgehog 'on' state 0.999999999987322 -1.26777117481009e-11 89 0 0 8 8608 R-MMU-573389 NoRC negatively regulates rRNA expression 0.999999999987322 -1.26777117481009e-11 89 0 0 8 8608 R-MMU-912497 Meiotic Recombination 0.999999999987322 -1.26777117481009e-11 89 0 0 8 8608 R-MMU-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 0.999999999987549 -1.24510381934123e-11 116 0 0 8 8608 R-MMU-199977 ER to Golgi Anterograde Transport 0.999999999987549 -1.24510381934123e-11 116 0 0 8 8608 R-MMU-418555 G alpha (s) signalling events 0.999999999987549 -1.24510381934123e-11 116 0 0 8 8608 R-MMU-6799198 Complex I biogenesis 0.999999999987564 -1.24359655750048e-11 49 0 0 8 8608 R-MMU-1638091 Heparan sulfate/heparin (HS-GAG) metabolism 0.999999999987564 -1.24359655750048e-11 49 0 0 8 8608 R-MMU-5362517 Signaling by Retinoic Acid 0.999999999987564 -1.24359655750048e-11 49 0 0 8 8608 R-MMU-1793185 Chondroitin sulfate/dermatan sulfate metabolism 0.999999999987564 -1.24359655750048e-11 49 0 0 8 8608 R-MMU-936837 Ion transport by P-type ATPases 0.999999999987564 -1.24359655750048e-11 49 0 0 8 8608 R-MMU-73894 DNA Repair 0.999999999987846 -1.21537339800935e-11 265 0 0 8 8608 R-MMU-1368110 Bmal1:Clock,Npas2 activates circadian gene expression 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-5205647 Mitophagy 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-1482801 Acyl chain remodelling of PS 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-5654688 SHC-mediated cascade:FGFR1 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-264876 Insulin processing 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-156584 Cytosolic sulfonation of small molecules 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-140875 Common Pathway of Fibrin Clot Formation 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-3000157 Laminin interactions 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-202131 Metabolism of nitric oxide 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-203765 eNOS activation and regulation 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-5205685 Pink/Parkin Mediated Mitophagy 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-69618 Mitotic Spindle Checkpoint 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-5654689 PI-3K cascade:FGFR1 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-445144 Signal transduction by L1 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-5357956 TNFR1-induced NFkappaB signaling pathway 0.999999999988611 -1.13894481500864e-11 21 0 0 8 8608 R-MMU-983705 Signaling by the B Cell Receptor (BCR) 0.999999999989393 -1.06070737993076e-11 201 0 0 8 8608 R-MMU-1592230 Mitochondrial biogenesis 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-5627123 RHO GTPases activate PAKs 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-1614635 Sulfur amino acid metabolism 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-975298 Ligand-gated ion channel transport 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-5654712 FRS-mediated FGFR4 signaling 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-182971 EGFR downregulation 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-6788467 IL-6-type cytokine receptor ligand interactions 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-1187000 Fertilization 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-2173789 TGF-beta receptor signaling activates SMADs 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-1679131 Trafficking and processing of endosomal TLR 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-69273 Cyclin A/B1 associated events during G2/M transition 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-77289 Mitochondrial Fatty Acid Beta-Oxidation 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-174048 APC/C:Cdc20 mediated degradation of Cyclin B 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-75876 Synthesis of very long-chain fatty acyl-CoAs 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-1474165 Reproduction 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-166208 mTORC1-mediated signalling 0.999999999989475 -1.05251752755289e-11 22 0 0 8 8608 R-MMU-453274 Mitotic G2-G2/M phases 0.999999999990214 -9.78631015591438e-12 166 0 0 8 8608 R-MMU-1236977 Endosomal/Vacuolar pathway 0.999999999990303 -9.69682536066561e-12 33 0 0 8 8608 R-MMU-5625886 Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 0.999999999990303 -9.69682536066561e-12 33 0 0 8 8608 R-MMU-5576892 Phase 0 - rapid depolarisation 0.999999999990303 -9.69682536066561e-12 33 0 0 8 8608 R-MMU-1980143 Signaling by NOTCH1 0.999999999990303 -9.69682536066561e-12 33 0 0 8 8608 R-MMU-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 0.999999999990303 -9.69682536066561e-12 33 0 0 8 8608 R-MMU-445355 Smooth Muscle Contraction 0.999999999990303 -9.69682536066561e-12 33 0 0 8 8608 R-MMU-3301854 Nuclear Pore Complex (NPC) Disassembly 0.999999999990303 -9.69682536066561e-12 33 0 0 8 8608 R-MMU-5654727 Negative regulation of FGFR2 signaling 0.999999999990303 -9.69682536066561e-12 33 0 0 8 8608 R-MMU-6783310 Fanconi Anemia Pathway 0.999999999990303 -9.69682536066561e-12 33 0 0 8 8608 R-MMU-391251 Protein folding 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-5689896 Ovarian tumor domain proteases 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-1855204 Synthesis of IP3 and IP4 in the cytosol 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-111996 Ca-dependent events 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-442742 CREB phosphorylation through the activation of Ras 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-5654732 Negative regulation of FGFR3 signaling 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-5694530 Cargo concentration in the ER 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-72086 mRNA Capping 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-380972 Energy dependent regulation of mTOR by LKB1-AMPK 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-75067 Processing of Capped Intronless Pre-mRNA 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-70171 Glycolysis 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-3000178 ECM proteoglycans 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-909733 Interferon alpha/beta signaling 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-917977 Transferrin endocytosis and recycling 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-390466 Chaperonin-mediated protein folding 0.999999999990477 -9.52295321104755e-12 28 0 0 8 8608 R-MMU-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 0.999999999990681 -9.31913616763952e-12 63 0 0 8 8608 R-MMU-6806834 Signaling by MET 0.999999999990681 -9.31913616763952e-12 63 0 0 8 8608 R-MMU-216083 Integrin cell surface interactions 0.999999999990681 -9.31913616763952e-12 63 0 0 8 8608 R-MMU-1632852 Macroautophagy 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-111885 Opioid Signalling 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-5607761 Dectin-1 mediated noncanonical NF-kB signaling 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-388841 Costimulation by the CD28 family 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-5610785 GLI3 is processed to GLI3R by the proteasome 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-5676590 NIK-->noncanonical NF-kB signaling 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-4608870 Asymmetric localization of PCP proteins 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-68827 CDT1 association with the CDC6:ORC:origin complex 0.999999999990829 -9.17104531486029e-12 58 0 0 8 8608 R-MMU-1266738 Developmental Biology 0.999999999991175 -8.82462404251797e-12 839 0 0 8 8608 R-MMU-72731 Recycling of eIF2:GDP 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-2995383 Initiation of Nuclear Envelope Reformation 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-210747 Regulation of gene expression in early pancreatic precursor cells 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-1483115 Hydrolysis of LPC 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-381038 XBP1(S) activates chaperone genes 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-389397 Orexin and neuropeptides FF and QRFP bind to their respective receptors 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-2161522 Abacavir transport and metabolism 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-140342 Apoptosis induced DNA fragmentation 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-198323 AKT phosphorylates targets in the cytosol 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-400451 Free fatty acids regulate insulin secretion 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-5625970 RHO GTPases activate KTN1 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-173623 Classical antibody-mediated complement activation 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-5652084 Fructose metabolism 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-112411 MAPK1 (ERK2) activation 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-201688 WNT mediated activation of DVL 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-211227 Activation of DNA fragmentation factor 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-1663150 The activation of arylsulfatases 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-450520 HuR (ELAVL1) binds and stabilizes mRNA 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-434316 Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-68952 DNA replication initiation 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-189085 Digestion of dietary carbohydrate 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-2995410 Nuclear Envelope Reassembly 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-1300644 Interaction With The Zona Pellucida 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-5576886 Phase 4 - resting membrane potential 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-193144 Estrogen biosynthesis 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-2046105 Linoleic acid (LA) metabolism 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-5357786 TNFR1-induced proapoptotic signaling 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-390696 Adrenoceptors 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-70635 Urea cycle 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-428930 Thromboxane signalling through TP receptor 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-8850843 Phosphate bond hydrolysis by NTPDase proteins 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-171007 p38MAPK events 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-448424 Interleukin-17 signaling 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-1250342 PI3K events in ERBB4 signaling 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-390471 Association of TriC/CCT with target proteins during biosynthesis 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-194313 VEGF ligand-receptor interactions 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-70921 Histidine catabolism 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-193634 Axonal growth inhibition (RHOA activation) 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-203927 MicroRNA (miRNA) biogenesis 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-1912408 Pre-NOTCH Transcription and Translation 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-427601 Multifunctional anion exchangers 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-166786 Creation of C4 and C2 activators 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-195399 VEGF binds to VEGFR leading to receptor dimerization 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-77111 Synthesis of Ketone Bodies 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-110329 Cleavage of the damaged pyrimidine 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-446210 Synthesis of UDP-N-acetyl-glucosamine 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-416550 Sema4D mediated inhibition of cell attachment and migration 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-174430 Telomere C-strand synthesis initiation 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-5658623 FGFRL1 modulation of FGFR1 signaling 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-2514853 Condensation of Prometaphase Chromosomes 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-190873 Gap junction degradation 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-73928 Depyrimidination 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-351906 Apoptotic cleavage of cell adhesion proteins 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-166665 Terminal pathway of complement 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-2393930 Phosphate bond hydrolysis by NUDT proteins 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-163765 ChREBP activates metabolic gene expression 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-190377 FGFR2b ligand binding and activation 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-8849469 PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-444821 Relaxin receptors 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-1236973 Cross-presentation of particulate exogenous antigens (phagosomes) 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-196108 Pregnenolone biosynthesis 0.999999999991318 -8.68228004008928e-12 8 0 0 8 8608 R-MMU-189445 Metabolism of porphyrins 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-1181150 Signaling by NODAL 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-442982 Ras activation uopn Ca2+ infux through NMDA receptor 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-196299 Beta-catenin phosphorylation cascade 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-3371571 HSF1-dependent transactivation 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-888590 GABA synthesis, release, reuptake and degradation 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-210745 Regulation of gene expression in beta cells 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-5674135 MAP2K and MAPK activation 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-6807004 Negative regulation of MET activity 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-114452 Activation of BH3-only proteins 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-190241 FGFR2 ligand binding and activation 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-1251985 Nuclear signaling by ERBB4 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-389357 CD28 dependent PI3K/Akt signaling 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-8874081 MET activates PTK2 signaling 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-110320 Translesion Synthesis by POLH 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-416700 Other semaphorin interactions 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-2559585 Oncogene Induced Senescence 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-5654710 PI-3K cascade:FGFR3 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-5654221 Phospholipase C-mediated cascade; FGFR2 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-5654704 SHC-mediated cascade:FGFR3 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-437239 Recycling pathway of L1 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-180024 DARPP-32 events 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-194223 HDL-mediated lipid transport 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-1912422 Pre-NOTCH Expression and Processing 0.999999999991642 -8.35811611731044e-12 18 0 0 8 8608 R-MMU-351202 Metabolism of polyamines 0.999999999992046 -7.95365549789633e-12 79 0 0 8 8608 R-MMU-975155 MyD88 dependent cascade initiated on endosome 0.999999999992046 -7.95365549789633e-12 79 0 0 8 8608 R-MMU-109704 PI3K Cascade 0.999999999992046 -7.95365549789633e-12 79 0 0 8 8608 R-MMU-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 0.999999999992046 -7.95365549789633e-12 79 0 0 8 8608 R-MMU-1221633 Meiotic Synapsis 0.999999999992052 -7.94796848244566e-12 104 0 0 8 8608 R-MMU-5250913 Positive epigenetic regulation of rRNA expression 0.999999999992052 -7.94796848244566e-12 104 0 0 8 8608 R-MMU-5693567 HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) 0.999999999992052 -7.94796848244566e-12 104 0 0 8 8608 R-MMU-1221632 Meiotic synapsis 0.999999999992052 -7.94796848244566e-12 104 0 0 8 8608 R-MMU-983168 Antigen processing: Ubiquitination & Proteasome degradation 0.999999999992158 -7.84148635388853e-12 149 0 0 8 8608 R-MMU-1299361 TWIK-related alkaline pH activated K+ channel (TALK) 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-156902 Peptide chain elongation 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-975574 Reactions specific to the hybrid N-glycan synthesis pathway 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-140180 COX reactions 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-211999 CYP2E1 reactions 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-1855231 Synthesis of IPs in the ER lumen 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-2142696 Synthesis of Hepoxilins (HX) and Trioxilins (TrX) 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-1483076 Synthesis of CL 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-379716 Cytosolic tRNA aminoacylation 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-379726 Mitochondrial tRNA aminoacylation 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-181429 Serotonin Neurotransmitter Release Cycle 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-190704 Oligomerization of connexins into connexons 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-6804754 Regulation of TP53 Expression 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-6806664 Metabolism of vitamin K 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-5263617 Metabolism of ingested MeSeO2H into MeSeH 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-1299344 TWIK-related spinal cord K+ channel (TRESK) 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-211994 Sterols are 12-hydroxylated by CYP8B1 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-1483196 PI and PC transport between ER and Golgi membranes 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-2408552 Methylation of MeSeH for excretion 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-389542 NADPH regeneration 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-2534343 Interaction With Cumulus Cells 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-5690714 CD22 mediated BCR regulation 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-1300645 Acrosome Reaction 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-198765 Signalling to ERK5 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-211957 Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-1299287 Tandem pore domain halothane-inhibited K+ channel (THIK) 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-111448 Activation of NOXA and translocation to mitochondria 0.999999999992174 -7.82590333682498e-12 1 0 0 8 8608 R-MMU-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-8864260 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-159418 Recycling of bile acids and salts 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-211935 Fatty acids 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-176412 Phosphorylation of the APC/C 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-912446 Meiotic recombination 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-77595 Processing of Intronless Pre-mRNAs 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-5620916 VxPx cargo-targeting to cilium 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-210993 Tie2 Signaling 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-450302 activated TAK1 mediates p38 MAPK activation 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-442660 Na+/Cl- dependent neurotransmitter transporters 0.999999999992211 -7.78918009110051e-12 19 0 0 8 8608 R-MMU-1236975 Antigen processing-Cross presentation 0.999999999992278 -7.72180223740498e-12 98 0 0 8 8608 R-MMU-1296071 Potassium Channels 0.999999999992278 -7.72180223740498e-12 98 0 0 8 8608 R-MMU-5668541 TNFR2 non-canonical NF-kB pathway 0.999999999992278 -7.72180223740498e-12 98 0 0 8 8608 R-MMU-73923 Lipid digestion, mobilization, and transport 0.999999999992278 -7.72180223740498e-12 98 0 0 8 8608 R-MMU-69239 Synthesis of DNA 0.999999999992278 -7.72180223740498e-12 98 0 0 8 8608 R-MMU-1500931 Cell-Cell communication 0.999999999992278 -7.72180223740498e-12 98 0 0 8 8608 R-MMU-425366 Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds 0.999999999992278 -7.72180223740498e-12 98 0 0 8 8608 R-MMU-2990846 SUMOylation 0.999999999992278 -7.72180223740498e-12 98 0 0 8 8608 R-MMU-5250941 Negative epigenetic regulation of rRNA expression 0.999999999992278 -7.72180223740498e-12 98 0 0 8 8608 R-MMU-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 0.99999999999242 -7.58014952669618e-12 127 0 0 8 8608 R-MMU-194840 Rho GTPase cycle 0.99999999999242 -7.58014952669618e-12 127 0 0 8 8608 R-MMU-5619507 Activation of HOX genes during differentiation 0.99999999999242 -7.58014952669618e-12 127 0 0 8 8608 R-MMU-166658 Complement cascade 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-991365 Activation of GABAB receptors 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-3769402 Deactivation of the beta-catenin transactivating complex 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-165159 mTOR signalling 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-140877 Formation of Fibrin Clot (Clotting Cascade) 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-5620924 Intraflagellar transport 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-429914 Deadenylation-dependent mRNA decay 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-425397 Transport of vitamins, nucleosides, and related molecules 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-1660662 Glycosphingolipid metabolism 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-5654741 Signaling by FGFR3 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-977444 GABA B receptor activation 0.999999999992919 -7.08052376593109e-12 39 0 0 8 8608 R-MMU-69202 Cyclin E associated events during G1/S transition 0.999999999993093 -6.90689960578592e-12 66 0 0 8 8608 R-MMU-5658442 Regulation of RAS by GAPs 0.999999999993093 -6.90689960578592e-12 66 0 0 8 8608 R-MMU-2559582 Senescence-Associated Secretory Phenotype (SASP) 0.999999999993093 -6.90689960578592e-12 66 0 0 8 8608 R-MMU-446728 Cell junction organization 0.999999999993093 -6.90689960578592e-12 66 0 0 8 8608 R-MMU-174154 APC/C:Cdc20 mediated degradation of Securin 0.999999999993093 -6.90689960578592e-12 66 0 0 8 8608 R-MMU-69656 Cyclin A:Cdk2-associated events at S phase entry 0.999999999993093 -6.90689960578592e-12 66 0 0 8 8608 R-MMU-2980736 Peptide hormone metabolism 0.999999999993093 -6.90689960578592e-12 66 0 0 8 8608 R-MMU-2151201 Transcriptional activation of mitochondrial biogenesis 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-202670 ERKs are inactivated 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-5626467 RHO GTPases activate IQGAPs 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-139853 Elevation of cytosolic Ca2+ levels 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-159854 Gamma-carboxylation, transport, and amino-terminal cleavage of proteins 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-5668599 RHO GTPases Activate NADPH Oxidases 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-190372 FGFR3c ligand binding and activation 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-190239 FGFR3 ligand binding and activation 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-167060 NGF processing 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-190375 FGFR2c ligand binding and activation 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-5633008 TP53 Regulates Transcription of Cell Death Genes 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-5654227 Phospholipase C-mediated cascade; FGFR3 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-3322077 Glycogen synthesis 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-2024101 CS/DS degradation 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-425561 Sodium/Calcium exchangers 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-418457 cGMP effects 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-2022377 Metabolism of Angiotensinogen to Angiotensins 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-1502540 Signaling by Activin 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-157858 Gap junction trafficking and regulation 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-977441 GABA A receptor activation 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-202040 G-protein activation 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-197264 Nicotinamide salvaging 0.999999999993365 -6.63547605591894e-12 13 0 0 8 8608 R-MMU-211945 Phase 1 - Functionalization of compounds 0.999999999993379 -6.62098136945937e-12 150 0 0 8 8608 R-MMU-5633007 Regulation of TP53 Activity 0.999999999993379 -6.62098136945937e-12 150 0 0 8 8608 R-MMU-5576891 Cardiac conduction 0.999999999993542 -6.45832960522677e-12 102 0 0 8 8608 R-MMU-2500257 Resolution of Sister Chromatid Cohesion 0.999999999993542 -6.45832960522677e-12 102 0 0 8 8608 R-MMU-190242 FGFR1 ligand binding and activation 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-5358508 Mismatch Repair 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-879518 Transport of organic anions 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-110312 Translesion synthesis by REV1 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-977068 Termination of O-glycan biosynthesis 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-1295596 Spry regulation of FGF signaling 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-2173788 Downregulation of TGF-beta receptor signaling 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-372708 p130Cas linkage to MAPK signaling for integrins 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-193048 Androgen biosynthesis 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-69183 Processive synthesis on the lagging strand 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-111931 PKA-mediated phosphorylation of CREB 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-549132 Organic cation/anion/zwitterion transport 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-381119 Unfolded Protein Response (UPR) 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-5099900 WNT5A-dependent internalization of FZD4 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-163615 PKA activation 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-5223345 Miscellaneous transport and binding events 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-975577 N-Glycan antennae elongation 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-156581 Methylation 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-70221 Glycogen breakdown (glycogenolysis) 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-1433559 Regulation of KIT signaling 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-1963642 PI3K events in ERBB2 signaling 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-392517 Rap1 signalling 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-2142845 Hyaluronan metabolism 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-193639 p75NTR signals via NF-kB 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-5635838 Activation of SMO 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-435354 Zinc transporters 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-8873719 RAB geranylgeranylation 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-5654228 Phospholipase C-mediated cascade; FGFR4 0.999999999993686 -6.31391401918135e-12 15 0 0 8 8608 R-MMU-5334727 Mus musculus biological processes 0.99999999999402 -5.97972834911127e-12 236 0 0 8 8608 R-MMU-5688426 Deubiquitination 0.99999999999402 -5.97972834911127e-12 236 0 0 8 8608 R-MMU-177929 Signaling by EGFR 0.999999999994178 -5.82183135625068e-12 312 0 0 8 8608 R-MMU-372790 Signaling by GPCR 0.999999999994296 -5.70438208189011e-12 1324 0 0 8 8608 R-MMU-453279 Mitotic G1-G1/S phases 0.99999999999441 -5.58952873163964e-12 131 0 0 8 8608 R-MMU-1428517 The citric acid (TCA) cycle and respiratory electron transport 0.99999999999441 -5.58952873163964e-12 131 0 0 8 8608 R-MMU-983231 Factors involved in megakaryocyte development and platelet production 0.999999999994666 -5.33395139723098e-12 115 0 0 8 8608 R-MMU-8856828 Clathrin-mediated endocytosis 0.999999999994666 -5.33395139723098e-12 115 0 0 8 8608 R-MMU-70153 Glucose transport 0.999999999994742 -5.25773359944813e-12 43 0 0 8 8608 R-MMU-6788656 Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism 0.999999999994742 -5.25773359944813e-12 43 0 0 8 8608 R-MMU-73893 DNA Damage Bypass 0.999999999994742 -5.25773359944813e-12 43 0 0 8 8608 R-MMU-1296072 Voltage gated Potassium channels 0.999999999994742 -5.25773359944813e-12 43 0 0 8 8608 R-MMU-2980766 Nuclear Envelope Breakdown 0.999999999994742 -5.25773359944813e-12 43 0 0 8 8608 R-MMU-975634 Retinoid metabolism and transport 0.999999999994742 -5.25773359944813e-12 43 0 0 8 8608 R-MMU-373076 Class A/1 (Rhodopsin-like receptors) 0.999999999994756 -5.24365980636079e-12 299 0 0 8 8608 R-MMU-388396 GPCR downstream signaling 0.999999999995509 -4.49072820020222e-12 1060 0 0 8 8608 R-MMU-418346 Platelet homeostasis 0.999999999995566 -4.43381676477776e-12 56 0 0 8 8608 R-MMU-1834949 Cytosolic sensors of pathogen-associated DNA 0.999999999995566 -4.43381676477776e-12 56 0 0 8 8608 R-MMU-4641258 Degradation of DVL 0.999999999995566 -4.43381676477776e-12 56 0 0 8 8608 R-MMU-5610780 Degradation of GLI1 by the proteasome 0.999999999995566 -4.43381676477776e-12 56 0 0 8 8608 R-MMU-432722 Golgi Associated Vesicle Biogenesis 0.999999999995566 -4.43381676477776e-12 56 0 0 8 8608 R-MMU-3371453 Regulation of HSF1-mediated heat shock response 0.999999999995566 -4.43381676477776e-12 56 0 0 8 8608 R-MMU-166054 Activated TLR4 signalling 0.999999999995684 -4.31580983737788e-12 80 0 0 8 8608 R-MMU-72766 Translation 0.99999999999572 -4.28029341890103e-12 119 0 0 8 8608 R-MMU-187687 Signalling to ERKs 0.999999999995906 -4.09441877681854e-12 226 0 0 8 8608 R-MMU-418594 G alpha (i) signalling events 0.999999999995918 -4.08245098649781e-12 205 0 0 8 8608 R-MMU-1250347 SHC1 events in ERBB4 signaling 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-3232118 SUMOylation of transcription factors 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-376176 Signaling by Robo receptor 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-1963640 GRB2 events in ERBB2 signaling 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-3000480 Scavenging by Class A Receptors 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-111447 Activation of BAD and translocation to mitochondria 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-446353 Cell-extracellular matrix interactions 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF) 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-1980150 Signaling by NOTCH4 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-193993 Mineralocorticoid biosynthesis 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-1980148 Signaling by NOTCH3 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-8847993 ERBB2 Activates PTK6 Signaling 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-400508 Incretin synthesis, secretion, and inactivation 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-1643685 Disease 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-622323 Presynaptic nicotinic acetylcholine receptors 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-428790 Facilitative Na+-independent glucose transporters 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-159782 Removal of aminoterminal propeptides from gamma-carboxylated proteins 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-71182 Phenylalanine and tyrosine catabolism 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-73817 Purine ribonucleoside monophosphate biosynthesis 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-877312 Regulation of IFNG signaling 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-451308 Activation of Ca-permeable Kainate Receptor 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-193807 Synthesis of bile acids and bile salts via 27-hydroxycholesterol 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-451306 Ionotropic activity of Kainate Receptors 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX) 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-202430 Translocation of ZAP-70 to Immunological synapse 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-2122947 NOTCH1 Intracellular Domain Regulates Transcription 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-8866427 VLDLR internalisation and degradation 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-209560 NF-kB is activated and signals survival 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-8863678 Neurodegenerative Diseases 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-6804759 Regulation of TP53 Activity through Association with Co-factors 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-1483213 Synthesis of PE 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-389359 CD28 dependent Vav1 pathway 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-209543 p75NTR recruits signalling complexes 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-71064 Lysine catabolism 0.999999999996147 -3.85319902457227e-12 12 0 0 8 8608 R-MMU-1482839 Acyl chain remodelling of PE 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-8863795 Downregulation of ERBB2 signaling 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-70268 Pyruvate metabolism 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-69190 DNA strand elongation 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-1169408 ISG15 antiviral mechanism 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-196807 Nicotinate metabolism 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-1169410 Antiviral mechanism by IFN-stimulated genes 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-73848 Pyrimidine metabolism 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-179409 APC-Cdc20 mediated degradation of Nek2A 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-174417 Telomere C-strand (Lagging Strand) Synthesis 0.999999999996269 -3.73107510696825e-12 24 0 0 8 8608 R-MMU-446203 Asparagine N-linked glycosylation 0.999999999996478 -3.52239903587632e-12 250 0 0 8 8608 R-MMU-881907 Gastrin-CREB signalling pathway via PKC and MAPK 0.999999999996507 -3.49302946678943e-12 390 0 0 8 8608 R-MMU-199418 Negative regulation of the PI3K/AKT network 0.999999999996582 -3.41808297831231e-12 91 0 0 8 8608 R-MMU-1433557 Signaling by SCF-KIT 0.999999999996601 -3.39867500753959e-12 289 0 0 8 8608 R-MMU-194441 Metabolism of non-coding RNA 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-157118 Signaling by NOTCH 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-383280 Nuclear Receptor transcription pathway 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-75815 Ubiquitin-dependent degradation of Cyclin D 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-69229 Ubiquitin-dependent degradation of Cyclin D1 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-5578775 Ion homeostasis 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-6781823 Formation of TC-NER Pre-Incision Complex 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-191859 snRNP Assembly 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-349425 Autodegradation of the E3 ubiquitin ligase COP1 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-350562 Regulation of ornithine decarboxylase (ODC) 0.999999999996691 -3.30896812576135e-12 51 0 0 8 8608 R-MMU-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 0.999999999996738 -3.26208224232177e-12 86 0 0 8 8608 R-MMU-5368287 Mitochondrial translation 0.999999999996738 -3.26208224232177e-12 86 0 0 8 8608 R-MMU-381753 Olfactory Signaling Pathway 0.99999999999696 -3.0397831105255e-12 534 0 0 8 8608 R-MMU-449147 Signaling by Interleukins 0.99999999999725 -2.75048524210047e-12 388 0 0 8 8608 R-MMU-5696398 Nucleotide Excision Repair 0.999999999997358 -2.64217085394021e-12 100 0 0 8 8608 R-MMU-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 0.999999999997385 -2.61476056907084e-12 114 0 0 8 8608 R-MMU-112316 Neuronal System 0.999999999997385 -2.61464387367212e-12 310 0 0 8 8608 R-MMU-4641257 Degradation of AXIN 0.999999999997551 -2.44901550886829e-12 54 0 0 8 8608 R-MMU-72702 Ribosomal scanning and start codon recognition 0.999999999997551 -2.44901550886829e-12 54 0 0 8 8608 R-MMU-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 0.999999999997551 -2.44901550886829e-12 54 0 0 8 8608 R-MMU-174113 SCF-beta-TrCP mediated degradation of Emi1 0.999999999997551 -2.44901550886829e-12 54 0 0 8 8608 R-MMU-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 0.999999999997551 -2.44901550886829e-12 54 0 0 8 8608 R-MMU-69541 Stabilization of p53 0.999999999997551 -2.44901550886829e-12 54 0 0 8 8608 R-MMU-1445148 Translocation of GLUT4 to the plasma membrane 0.999999999997551 -2.44901550886829e-12 54 0 0 8 8608 R-MMU-3928665 EPH-ephrin mediated repulsion of cells 0.999999999997577 -2.42306079202252e-12 37 0 0 8 8608 R-MMU-3928662 EPHB-mediated forward signaling 0.999999999997577 -2.42306079202252e-12 37 0 0 8 8608 R-MMU-176187 Activation of ATR in response to replication stress 0.999999999997577 -2.42306079202252e-12 37 0 0 8 8608 R-MMU-6811438 Intra-Golgi traffic 0.999999999997577 -2.42306079202252e-12 37 0 0 8 8608 R-MMU-5685938 HDR through Single Strand Annealing (SSA) 0.999999999997577 -2.42306079202252e-12 37 0 0 8 8608 R-MMU-1566948 Elastic fibre formation 0.999999999997577 -2.42306079202252e-12 37 0 0 8 8608 R-MMU-5620920 Cargo trafficking to the periciliary membrane 0.999999999997577 -2.42306079202252e-12 37 0 0 8 8608 R-MMU-1799339 SRP-dependent cotranslational protein targeting to membrane 0.999999999997655 -2.34529567027266e-12 78 0 0 8 8608 R-MMU-8856688 Golgi-to-ER retrograde transport 0.999999999997655 -2.34529567027266e-12 78 0 0 8 8608 R-MMU-68875 Mitotic Prophase 0.999999999997655 -2.34529567027266e-12 78 0 0 8 8608 R-MMU-68886 M Phase 0.999999999997698 -2.30200099105124e-12 246 0 0 8 8608 R-MMU-6811434 COPI-dependent Golgi-to-ER retrograde traffic 0.99999999999785 -2.14984627216372e-12 52 0 0 8 8608 R-MMU-69613 p53-Independent G1/S DNA damage checkpoint 0.99999999999785 -2.14984627216372e-12 52 0 0 8 8608 R-MMU-72165 mRNA Splicing - Minor Pathway 0.99999999999785 -2.14984627216372e-12 52 0 0 8 8608 R-MMU-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 0.99999999999785 -2.14984627216372e-12 52 0 0 8 8608 R-MMU-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 0.99999999999785 -2.14984627216372e-12 52 0 0 8 8608 R-MMU-69610 p53-Independent DNA Damage Response 0.99999999999785 -2.14984627216372e-12 52 0 0 8 8608 R-MMU-193648 NRAGE signals death through JNK 0.99999999999785 -2.14984627216372e-12 52 0 0 8 8608 R-MMU-6805567 Keratinization 0.999999999998177 -1.82265821166466e-12 141 0 0 8 8608 R-MMU-535734 Fatty acid, triacylglycerol, and ketone body metabolism 0.999999999998177 -1.82265821166466e-12 141 0 0 8 8608 R-MMU-382551 Transmembrane transport of small molecules 0.999999999998407 -1.59250102562958e-12 622 0 0 8 8608 R-MMU-190370 FGFR1b ligand binding and activation 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-163680 AMPK inhibits chREBP transcriptional activation activity 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-6798163 Choline catabolism 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-879415 Advanced glycosylation endproduct receptor signaling 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-2142688 Synthesis of 5-eicosatetraenoic acids 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-388479 Vasopressin-like receptors 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-5674499 Negative feedback regulation of MAPK pathway 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-6806942 MET Receptor Activation 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-211916 Vitamins 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-5676934 Protein repair 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-5626978 TNFR1-mediated ceramide production 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-6787639 GDP-fucose biosynthesis 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-196783 Coenzyme A biosynthesis 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-8857538 PTK6 promotes HIF1A stabilization 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-420597 Nectin/Necl trans heterodimerization 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-5693548 Sensing of DNA Double Strand Breaks 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-176417 Phosphorylation of Emi1 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-74713 IRS activation 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-5632681 Ligand-receptor interactions 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-448706 Interleukin-1 processing 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-211979 Eicosanoids 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-947581 Molybdenum cofactor biosynthesis 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-447043 Neurofascin interactions 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-72764 Eukaryotic Translation Termination 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-435368 Zinc efflux and compartmentalization by the SLC30 family 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-70350 Fructose catabolism 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-8935690 Miscellaneous digestion events 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-442717 CREB phosphorylation through the activation of CaMKK 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-5358493 Synthesis of diphthamide-EEF2 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-111957 Cam-PDE 1 activation 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-8851907 MET activates PI3K/AKT signaling 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-446199 Synthesis of Dolichyl-phosphate 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-500657 Presynaptic function of Kainate receptors 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-433692 Proton-coupled monocarboxylate transport 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-444257 RSK activation 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-6783783 Interleukin-10 signaling 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-3065679 SUMO is proteolytically processed 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-68616 Assembly of the ORC complex at the origin of replication 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-212676 Dopamine Neurotransmitter Release Cycle 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-500753 Pyrimidine biosynthesis 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-3371511 HSF1 activation 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-110362 POLB-Dependent Long Patch Base Excision Repair 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-2428933 SHC-related events triggered by IGF1R 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-196843 Vitamin B2 (riboflavin) metabolism 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-5649702 APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-205025 NADE modulates death signalling 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-174362 Transport and synthesis of PAPS 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-2142770 Synthesis of 15-eicosatetraenoic acid derivatives 0.999999999998586 -1.41405938451514e-12 6 0 0 8 8608 R-MMU-1169091 Activation of NF-kappaB in B cells 0.999999999998663 -1.33679399305517e-12 65 0 0 8 8608 R-MMU-1253288 Downregulation of ERBB4 signaling 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-629587 Highly sodium permeable acetylcholine nicotinic receptors 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-189483 Heme degradation 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-426496 Post-transcriptional silencing by small RNAs 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-1234158 Regulation of gene expression by Hypoxia-inducible Factor 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-112311 Neurotransmitter Clearance In The Synaptic Cleft 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-392170 ADP signalling through P2Y purinoceptor 12 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-162791 Attachment of GPI anchor to uPAR 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-5576894 Phase 1 - inactivation of fast Na+ channels 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-196025 Formation of annular gap junctions 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-2408522 Selenoamino acid metabolism 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-4641265 Repression of WNT target genes 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-1482883 Acyl chain remodeling of DAG and TAG 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-1614558 Degradation of cysteine and homocysteine 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-426117 Cation-coupled Chloride cotransporters 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-71288 Creatine metabolism 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-1461973 Defensins 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-190371 FGFR3b ligand binding and activation 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-111471 Apoptotic factor-mediated response 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-447041 CHL1 interactions 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-390247 Beta-oxidation of very long chain fatty acids 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-111453 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-6814848 Glycerophospholipid catabolism 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-1461957 Beta defensins 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-2214320 Anchoring fibril formation 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-196791 Vitamin D (calciferol) metabolism 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-1483148 Synthesis of PG 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-199920 CREB phosphorylation 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-8937144 Aryl hydrocarbon receptor signalling 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-196836 Vitamin C (ascorbate) metabolism 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-5689877 Josephin domain DUBs 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-198693 AKT phosphorylates targets in the nucleus 0.999999999998773 -1.22720301202779e-12 7 0 0 8 8608 R-MMU-382556 ABC-family proteins mediated transport 0.999999999998888 -1.11237782024379e-12 96 0 0 8 8608 R-MMU-210500 Glutamate Neurotransmitter Release Cycle 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-198725 Nuclear Events (kinase and transcription factor activation) 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-5621575 CD209 (DC-SIGN) signaling 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-499943 Synthesis and interconversion of nucleotide di- and triphosphates 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-400042 Adrenaline,noradrenaline inhibits insulin secretion 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-933541 TRAF6 mediated IRF7 activation 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-2142670 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-140837 Intrinsic Pathway of Fibrin Clot Formation 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-8855121 VLDL interactions 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-419037 NCAM1 interactions 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-5654693 FRS-mediated FGFR1 signaling 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-425410 Metal ion SLC transporters 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-373752 Netrin-1 signaling 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-5654695 PI-3K cascade:FGFR2 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-5576893 Phase 2 - plateau phase 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-70895 Branched-chain amino acid catabolism 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-201451 Signaling by BMP 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-5654699 SHC-mediated cascade:FGFR2 0.999999999998889 -1.11134667899307e-12 23 0 0 8 8608 R-MMU-983712 Ion channel transport 0.999999999999368 -6.32312176832018e-13 186 0 0 8 8608 R-MMU-5693538 Homology Directed Repair 0.999999999999485 -5.14773598485215e-13 109 0 0 8 8608 R-MMU-1280215 Cytokine Signaling in Immune system 0.999999999999628 -3.72413203121655e-13 510 0 0 8 8608 R-MMU-375276 Peptide ligand-binding receptors 0.999999999999636 -3.64366909655147e-13 187 0 0 8 8608 R-MMU-180336 SHC1 events in EGFR signaling 0.999999999999872 -1.28062867281092e-13 213 0 0 8 8608 R-MMU-5673001 RAF/MAP kinase cascade 0.999999999999872 -1.28062867281092e-13 213 0 0 8 8608 R-MMU-179812 GRB2 events in EGFR signaling 0.999999999999872 -1.28062867281092e-13 213 0 0 8 8608 R-MMU-187706 Signalling to p38 via RIT and RIN 0.999999999999872 -1.28062867281092e-13 213 0 0 8 8608 R-MMU-112412 SOS-mediated signalling 0.999999999999872 -1.28062867281092e-13 213 0 0 8 8608 R-MMU-4086398 Ca2+ pathway 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-163359 Glucagon signaling in metabolic regulation 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-352230 Amino acid transport across the plasma membrane 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-73884 Base Excision Repair 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-5693537 Resolution of D-Loop Structures 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-113418 Formation of the Early Elongation Complex 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-1222556 ROS, RNS production in phagocytes 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-4085001 Sialic acid metabolism 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-192105 Synthesis of bile acids and bile salts 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-397795 G-protein beta:gamma signalling 0.999999999999921 -7.88774456548805e-14 32 0 0 8 8608 R-MMU-442755 Activation of NMDA receptor upon glutamate binding and postsynaptic events 1.00000000000006 5.98711330719811e-14 38 0 0 8 8608 R-MMU-5693606 DNA Double Strand Break Response 1.00000000000017 1.69077219692915e-13 53 0 0 8 8608 R-MMU-168928 RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways 1.00000000000017 1.69077219692915e-13 53 0 0 8 8608 R-MMU-72649 Translation initiation complex formation 1.00000000000017 1.69077219692915e-13 53 0 0 8 8608 R-MMU-6809371 Formation of the cornified envelope 1.00000000000017 1.69077219692915e-13 53 0 0 8 8608 R-MMU-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 1.00000000000017 1.69077219692915e-13 53 0 0 8 8608 R-MMU-73930 Abasic sugar-phosphate removal via the single-nucleotide replacement pathway 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-205017 NFG and proNGF binds to p75NTR 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-380612 Metabolism of serotonin 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-171319 Telomere Extension By Telomerase 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-432030 Transport of glycerol from adipocytes to the liver by Aquaporins 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-379724 tRNA Aminoacylation 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-177128 Conjugation of salicylate with glycine 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-452723 Transcriptional regulation of pluripotent stem cells 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-916853 Degradation of GABA 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-73843 5-Phosphoribose 1-diphosphate biosynthesis 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-5652227 Fructose biosynthesis 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-187015 Activation of TRKA receptors 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-177162 Conjugation of phenylacetate with glutamine 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-379398 Enzymatic degradation of Dopamine by monoamine oxidase 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-8854521 Interaction between PHLDA1 and AURKA 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-190872 Transport of connexons to the plasma membrane 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-69895 Transcriptional activation of cell cycle inhibitor p21 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-428559 Proton-coupled neutral amino acid transporters 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-163316 Mitochondrial transcription termination 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-114294 Activation, translocation and oligomerization of BAX 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-888568 GABA synthesis 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-392023 Adrenaline signalling through Alpha-2 adrenergic receptor 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-1483152 Hydrolysis of LPE 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-75896 Plasmalogen biosynthesis 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-480985 Synthesis of dolichyl-phosphate-glucose 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-141424 Amplification of signal from the kinetochores 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-165160 PDE3B signalling 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-69560 Transcriptional activation of p53 responsive genes 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-141333 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-5357572 Lysosomal glycogen catabolism 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-163754 Insulin effects increased synthesis of Xylulose-5-Phosphate 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-111452 Activation and oligomerization of BAK protein 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-1614603 Cysteine formation from homocysteine 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-211163 AKT-mediated inactivation of FOXO1A 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-68881 Mitotic Metaphase/Anaphase Transition 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-111995 phospho-PLA2 pathway 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-75102 C6 deamination of adenosine 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-73942 DNA Damage Reversal 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-75094 Formation of the Editosome 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-3296197 Hydroxycarboxylic acid-binding receptors 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-379397 Enzymatic degradation of dopamine by COMT 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-187042 TRKA activation by NGF 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-70688 Proline catabolism 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-166020 Transfer of LPS from LBP carrier to CD14 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-141334 PAOs oxidise polyamines to amines 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-203754 NOSIP mediated eNOS trafficking 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-72200 mRNA Editing: C to U Conversion 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-111457 Release of apoptotic factors from the mitochondria 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-163358 PKA-mediated phosphorylation of key metabolic factors 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-71737 Pyrophosphate hydrolysis 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-1369007 Mitochondrial ABC transporters 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-1300652 Sperm:Oocyte Membrane Binding 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-2408557 Selenocysteine synthesis 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-77042 Formation of editosomes by ADAR proteins 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-169911 Regulation of Apoptosis 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-381042 PERK regulates gene expression 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-75064 mRNA Editing: A to I Conversion 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-1483101 Synthesis of PS 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-351143 Agmatine biosynthesis 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-446343 Localization of the PINCH-ILK-PARVIN complex to focal adhesions 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-73943 Reversal of alkylation damage by DNA dioxygenases 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-1299316 TWIK-releated acid-sensitive K+ channel (TASK) 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-451307 Activation of Na-permeable Kainate Receptors 1.0000000000004 3.95011565973689e-13 2 0 0 8 8608 R-MMU-68877 Mitotic Prometaphase 1.00000000000046 4.59878855406196e-13 110 0 0 8 8608 R-MMU-69206 G1/S Transition 1.00000000000046 4.59878855406196e-13 110 0 0 8 8608 R-MMU-504046 RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription 1.00000000000046 4.59878855406196e-13 110 0 0 8 8608 R-MMU-1257604 PIP3 activates AKT signaling 1.00000000000046 4.59878855406196e-13 110 0 0 8 8608 R-MMU-2467813 Separation of Sister Chromatids 1.00000000000048 4.81479644946193e-13 165 0 0 8 8608 R-MMU-1483257 Phospholipid metabolism 1.0000000000006 6.01690795709348e-13 190 0 0 8 8608 R-MMU-5689880 Ub-specific processing proteases 1.00000000000061 6.09859101086574e-13 171 0 0 8 8608 R-MMU-68882 Mitotic Anaphase 1.00000000000061 6.09859101086574e-13 171 0 0 8 8608 R-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 1.00000000000061 6.12767665450513e-13 97 0 0 8 8608 R-MMU-927802 Nonsense-Mediated Decay (NMD) 1.00000000000061 6.12767665450513e-13 97 0 0 8 8608 R-MMU-397014 Muscle contraction 1.00000000000066 6.6037139492696e-13 158 0 0 8 8608 R-MMU-380287 Centrosome maturation 1.00000000000079 7.8823417881693e-13 75 0 0 8 8608 R-MMU-69473 G2/M DNA damage checkpoint 1.00000000000079 7.8823417881693e-13 75 0 0 8 8608 R-MMU-69304 Regulation of DNA replication 1.00000000000079 7.8823417881693e-13 75 0 0 8 8608 R-MMU-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 1.00000000000079 7.8823417881693e-13 75 0 0 8 8608 R-MMU-380270 Recruitment of mitotic centrosome proteins and complexes 1.00000000000079 7.8823417881693e-13 75 0 0 8 8608 R-MMU-3214847 HATs acetylate histones 1.00000000000079 7.8823417881693e-13 75 0 0 8 8608 R-MMU-174084 Autodegradation of Cdh1 by Cdh1:APC/C 1.00000000000097 9.7394980513949e-13 62 0 0 8 8608 R-MMU-1650814 Collagen biosynthesis and modifying enzymes 1.00000000000097 9.7394980513949e-13 62 0 0 8 8608 R-MMU-69580 p53-Dependent G1/S DNA damage checkpoint 1.00000000000097 9.7394980513949e-13 62 0 0 8 8608 R-MMU-69563 p53-Dependent G1 DNA Damage Response 1.00000000000097 9.7394980513949e-13 62 0 0 8 8608 R-MMU-977443 GABA receptor activation 1.00000000000104 1.04247807962849e-12 55 0 0 8 8608 R-MMU-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 1.00000000000104 1.04247807962849e-12 55 0 0 8 8608 R-MMU-72187 mRNA 3'-end processing 1.00000000000104 1.04247807962849e-12 55 0 0 8 8608 R-MMU-373755 Semaphorin interactions 1.00000000000104 1.04247807962849e-12 55 0 0 8 8608 R-MMU-373080 Class B/2 (Secretin family receptors) 1.00000000000104 1.04247807962849e-12 55 0 0 8 8608 R-MMU-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 1.00000000000109 1.08910975362881e-12 77 0 0 8 8608 R-MMU-156580 Phase II conjugation 1.00000000000109 1.08910975362881e-12 77 0 0 8 8608 R-MMU-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 1.00000000000109 1.08910975362881e-12 77 0 0 8 8608 R-MMU-73864 RNA Polymerase I Transcription 1.00000000000109 1.08910975362881e-12 77 0 0 8 8608 R-MMU-195253 Degradation of beta-catenin by the destruction complex 1.00000000000109 1.08910975362881e-12 77 0 0 8 8608 R-MMU-1500620 Meiosis 1.00000000000115 1.1460176148286e-12 121 0 0 8 8608 R-MMU-3108232 SUMO E3 ligases SUMOylate target proteins 1.00000000000118 1.17518361487502e-12 92 0 0 8 8608 R-MMU-211958 Miscellaneous substrates 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-937042 IRAK2 mediated activation of TAK1 complex 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-110357 Displacement of DNA glycosylase by APEX1 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-2179392 EGFR Transactivation by Gastrin 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-1296052 Ca2+ activated K+ channels 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-193697 p75NTR regulates axonogenesis 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-75892 Platelet Adhesion to exposed collagen 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-110056 MAPK3 (ERK1) activation 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-937039 IRAK1 recruits IKK complex 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-209822 Glycoprotein hormones 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-429947 Deadenylation of mRNA 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-3772470 Negative regulation of TCF-dependent signaling by WNT ligand antagonists 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-4419969 Depolymerisation of the Nuclear Lamina 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-2485179 Activation of the phototransduction cascade 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-629597 Highly calcium permeable nicotinic acetylcholine receptors 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-77286 mitochondrial fatty acid beta-oxidation of saturated fatty acids 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-162658 Golgi Cisternae Pericentriolar Stack Reorganization 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-1362409 Mitochondrial iron-sulfur cluster biogenesis 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-1368082 RORA activates gene expression 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-381070 IRE1alpha activates chaperones 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-432142 Platelet sensitization by LDL 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-727802 Transport of nucleotide sugars 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-74182 Ketone body metabolism 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-8875656 MET receptor recycling 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-5607763 CLEC7A (Dectin-1) induces NFAT activation 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-391908 Prostanoid ligand receptors 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-5685939 HDR through MMEJ (alt-NHEJ) 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-975578 Reactions specific to the complex N-glycan synthesis pathway 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-6811555 PI5P Regulates TP53 Acetylation 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-174403 Glutathione synthesis and recycling 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-3270619 IRF3-mediated induction of type I IFN 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-446107 Type I hemidesmosome assembly 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-425986 Sodium/Proton exchangers 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-442380 Zinc influx into cells by the SLC39 gene family 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-445095 Interaction between L1 and Ankyrins 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 1.00000000000125 1.25411760371181e-12 9 0 0 8 8608 R-MMU-1483206 Glycerophospholipid biosynthesis 1.00000000000127 1.26705886812743e-12 120 0 0 8 8608 R-MMU-425407 SLC-mediated transmembrane transport 1.0000000000013 1.29614721164127e-12 274 0 0 8 8608 R-MMU-8848021 Signaling by PTK6 1.00000000000138 1.37658333449107e-12 57 0 0 8 8608 R-MMU-195258 RHO GTPase Effectors 1.0000000000014 1.4036446099435e-12 244 0 0 8 8608 R-MMU-5656169 Termination of translesion DNA synthesis 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-167021 PLC-gamma1 signalling 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-2299718 Condensation of Prophase Chromosomes 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-354192 Integrin alphaIIb beta3 signaling 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-5654716 Downstream signaling of activated FGFR4 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-1489509 DAG and IP3 signaling 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-2426168 Activation of gene expression by SREBF (SREBP) 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-77387 Insulin receptor recycling 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-2022928 HS-GAG biosynthesis 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-2142816 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-418360 Platelet calcium homeostasis 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-1483191 Synthesis of PC 1.0000000000017 1.69661310688874e-12 27 0 0 8 8608 R-MMU-381340 Transcriptional regulation of white adipocyte differentiation 1.00000000000189 1.89103862544172e-12 59 0 0 8 8608 R-MMU-187577 SCF(Skp2)-mediated degradation of p27/p21 1.00000000000189 1.89103862544172e-12 59 0 0 8 8608 R-MMU-6803157 Antimicrobial peptides 1.00000000000189 1.89103862544172e-12 59 0 0 8 8608 R-MMU-6782135 Dual incision in TC-NER 1.00000000000189 1.89103862544172e-12 59 0 0 8 8608 R-MMU-450294 MAP kinase activation in TLR cascade 1.00000000000189 1.89103862544172e-12 59 0 0 8 8608 R-MMU-442533 Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes 1.00000000000189 1.89103862544172e-12 59 0 0 8 8608 R-MMU-416482 G alpha (12/13) signalling events 1.00000000000189 1.89103862544172e-12 59 0 0 8 8608 R-MMU-5250924 B-WICH complex positively regulates rRNA expression 1.00000000000189 1.89103862544172e-12 59 0 0 8 8608 R-MMU-1630316 Glycosaminoglycan metabolism 1.00000000000191 1.90849416238587e-12 113 0 0 8 8608 R-MMU-198203 PI3K/AKT activation 1.00000000000191 1.90849416238587e-12 113 0 0 8 8608 R-MMU-180292 GAB1 signalosome 1.00000000000191 1.90849416238587e-12 113 0 0 8 8608 R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 1.00000000000191 1.90849416238587e-12 113 0 0 8 8608 R-MMU-8868773 rRNA processing in the nucleus and cytosol 1.00000000000191 1.90849416238587e-12 113 0 0 8 8608 R-MMU-72312 rRNA processing 1.00000000000191 1.90849416238587e-12 113 0 0 8 8608 R-MMU-5578749 Transcriptional regulation by small RNAs 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-69300 Removal of licensing factors from origins 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-3371556 Cellular response to heat stress 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-199992 trans-Golgi Network Vesicle Budding 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-421837 Clathrin derived vesicle budding 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-3108214 SUMOylation of DNA damage response and repair proteins 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-422356 Regulation of insulin secretion 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-2142753 Arachidonic acid metabolism 1.00000000000202 2.01770686281712e-12 72 0 0 8 8608 R-MMU-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) 1.00000000000208 2.07914045863007e-12 267 0 0 8 8608 R-MMU-5653656 Vesicle-mediated transport 1.00000000000213 2.12898459750288e-12 539 0 0 8 8608 R-MMU-6804758 Regulation of TP53 Activity through Acetylation 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-912694 Regulation of IFNA signaling 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-6811436 COPI-independent Golgi-to-ER retrograde traffic 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-111933 Calmodulin induced events 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-1266695 Interleukin-7 signaling 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-5218920 VEGFR2 mediated vascular permeability 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-375170 CDO in myogenesis 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-111997 CaM pathway 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-77075 RNA Pol II CTD phosphorylation and interaction with CE 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-210991 Basigin interactions 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-114508 Effects of PIP2 hydrolysis 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-157579 Telomere Maintenance 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-6803529 FGFR2 alternative splicing 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-2022854 Keratan sulfate biosynthesis 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-525793 Myogenesis 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-2871809 FCERI mediated Ca+2 mobilization 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-1482788 Acyl chain remodelling of PC 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-1971475 A tetrasaccharide linker sequence is required for GAG synthesis 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-977606 Regulation of Complement cascade 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-113510 E2F mediated regulation of DNA replication 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-180786 Extension of Telomeres 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-3238698 WNT ligand biogenesis and trafficking 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-156590 Glutathione conjugation 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-202433 Generation of second messenger molecules 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-211976 Endogenous sterols 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-5673000 RAF activation 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-5669034 TNFs bind their physiological receptors 1.00000000000216 2.16292377485932e-12 26 0 0 8 8608 R-MMU-1852241 Organelle biogenesis and maintenance 1.0000000000022 2.19843586982272e-12 276 0 0 8 8608 R-MMU-74751 Insulin receptor signalling cascade 1.00000000000247 2.4727926007558e-12 266 0 0 8 8608 R-MMU-2428924 IGF1R signaling cascade 1.00000000000247 2.4727926007558e-12 266 0 0 8 8608 R-MMU-2428928 IRS-related events triggered by IGF1R 1.00000000000247 2.4727926007558e-12 266 0 0 8 8608 R-MMU-1660661 Sphingolipid de novo biosynthesis 1.00000000000249 2.48517672096875e-12 45 0 0 8 8608 R-MMU-4570464 SUMOylation of RNA binding proteins 1.00000000000249 2.48517672096875e-12 45 0 0 8 8608 R-MMU-421270 Cell-cell junction organization 1.00000000000249 2.48517672096875e-12 45 0 0 8 8608 R-MMU-69242 S Phase 1.00000000000261 2.60912544748569e-12 124 0 0 8 8608 R-MMU-2022090 Assembly of collagen fibrils and other multimeric structures 1.0000000000027 2.70462364173097e-12 40 0 0 8 8608 R-MMU-5696395 Formation of Incision Complex in GG-NER 1.0000000000027 2.70462364173097e-12 40 0 0 8 8608 R-MMU-109703 PKB-mediated events 1.0000000000027 2.70462364173097e-12 40 0 0 8 8608 R-MMU-5654743 Signaling by FGFR4 1.0000000000027 2.70462364173097e-12 40 0 0 8 8608 R-MMU-1227986 Signaling by ERBB2 1.0000000000027 2.70462364173097e-12 40 0 0 8 8608 R-MMU-112043 PLC beta mediated events 1.0000000000027 2.70462364173097e-12 40 0 0 8 8608 R-MMU-5358346 Hedgehog ligand biogenesis 1.00000000000339 3.39481629764909e-12 61 0 0 8 8608 R-MMU-913531 Interferon Signaling 1.00000000000339 3.39481629764909e-12 61 0 0 8 8608 R-MMU-5687128 MAPK6/MAPK4 signaling 1.00000000000346 3.45634041746578e-12 74 0 0 8 8608 R-MMU-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 1.00000000000346 3.45634041746578e-12 74 0 0 8 8608 R-MMU-2871837 FCERI mediated NF-kB activation 1.00000000000346 3.45634041746578e-12 74 0 0 8 8608 R-MMU-202427 Phosphorylation of CD3 and TCR zeta chains 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-181431 Acetylcholine Binding And Downstream Events 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-1369062 ABC transporters in lipid homeostasis 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-399954 Sema3A PAK dependent Axon repulsion 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-74217 Purine salvage 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-430039 mRNA decay by 5' to 3' exoribonuclease 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-5682910 LGI-ADAM interactions 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-418597 G alpha (z) signalling events 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-6785631 ERBB2 Regulates Cell Motility 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-170670 Adenylate cyclase inhibitory pathway 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-418359 Reduction of cytosolic Ca++ levels 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-163560 Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-68884 Mitotic Telophase/Cytokinesis 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-629602 Activation of Nicotinic Acetylcholine Receptors 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-194002 Glucocorticoid biosynthesis 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-190322 FGFR4 ligand binding and activation 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-204174 Regulation of pyruvate dehydrogenase (PDH) complex 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-997269 Inhibition of adenylate cyclase pathway 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-6785807 Interleukin-4 and 13 signaling 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-1660516 Synthesis of PIPs at the early endosome membrane 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-69109 Leading Strand Synthesis 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-391903 Eicosanoid ligand-binding receptors 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-69166 Removal of the Flap Intermediate 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-69091 Polymerase switching 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-622327 Postsynaptic nicotinic acetylcholine receptors 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-416572 Sema4D induced cell migration and growth-cone collapse 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-1250196 SHC1 events in ERBB2 signaling 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-174411 Polymerase switching on the C-strand of the telomere 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-1810476 RIP-mediated NFkB activation via ZBP1 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-2046106 alpha-linolenic acid (ALA) metabolism 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-69298 Association of licensing factors with the pre-replicative complex 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-3000170 Syndecan interactions 1.00000000000347 3.4721790805706e-12 14 0 0 8 8608 R-MMU-3214841 PKMTs methylate histone lysines 1.00000000000354 3.53694765321333e-12 69 0 0 8 8608 R-MMU-204998 Cell death signalling via NRAGE, NRIF and NADE 1.00000000000354 3.53694765321333e-12 69 0 0 8 8608 R-MMU-1640170 Cell Cycle 1.00000000000376 3.76471543925701e-12 591 0 0 8 8608 R-MMU-416476 G alpha (q) signalling events 1.00000000000381 3.81435551324662e-12 170 0 0 8 8608 R-MMU-975871 MyD88 cascade initiated on plasma membrane 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-168142 Toll Like Receptor 10 (TLR10) Cascade 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-168176 Toll Like Receptor 5 (TLR5) Cascade 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-5693607 Processing of DNA double-strand break ends 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-427389 ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-166058 MyD88:Mal cascade initiated on plasma membrane 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-181438 Toll Like Receptor 2 (TLR2) Cascade 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-1474290 Collagen formation 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-168179 Toll Like Receptor TLR1:TLR2 Cascade 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-5696399 Global Genome Nucleotide Excision Repair (GG-NER) 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-168188 Toll Like Receptor TLR6:TLR2 Cascade 1.00000000000394 3.93881028061182e-12 73 0 0 8 8608 R-MMU-422475 Axon guidance 1.00000000000421 4.2089921038577e-12 436 0 0 8 8608 R-MMU-556833 Metabolism of lipids and lipoproteins 1.00000000000432 4.31538139518562e-12 697 0 0 8 8608 R-MMU-72737 Cap-dependent Translation Initiation 1.00000000000444 4.4369045637171e-12 101 0 0 8 8608 R-MMU-72613 Eukaryotic Translation Initiation 1.00000000000444 4.4369045637171e-12 101 0 0 8 8608 R-MMU-202733 Cell surface interactions at the vascular wall 1.00000000000444 4.4369045637171e-12 101 0 0 8 8608 R-MMU-211000 Gene Silencing by RNA 1.00000000000444 4.4369045637171e-12 101 0 0 8 8608 R-MMU-6804756 Regulation of TP53 Activity through Phosphorylation 1.00000000000452 4.52123414715898e-12 90 0 0 8 8608 R-MMU-427413 NoRC negatively regulates rRNA expression 1.00000000000452 4.52123414715898e-12 90 0 0 8 8608 R-MMU-5654733 Negative regulation of FGFR4 signaling 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-399719 Trafficking of AMPA receptors 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-186712 Regulation of beta-cell development 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-70263 Gluconeogenesis 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-5654696 Downstream signaling of activated FGFR2 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-6794361 Interactions of neurexins and neuroligins at synapses 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-2514859 Inactivation, recovery and regulation of the phototransduction cascade 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-73772 RNA Polymerase I Promoter Escape 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-212718 EGFR interacts with phospholipase C-gamma 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-1638074 Keratan sulfate/keratin metabolism 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-399721 Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-420092 Glucagon-type ligand receptors 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-2129379 Molecules associated with elastic fibres 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-3000171 Non-integrin membrane-ECM interactions 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-390918 Peroxisomal lipid metabolism 1.00000000000464 4.64133892688485e-12 30 0 0 8 8608 R-MMU-74752 Signaling by Insulin receptor 1.00000000000468 4.67788962330421e-12 290 0 0 8 8608 R-MMU-5610787 Hedgehog 'off' state 1.00000000000486 4.86418525205092e-12 93 0 0 8 8608 R-MMU-166016 Toll Like Receptor 4 (TLR4) Cascade 1.00000000000486 4.86418525205092e-12 93 0 0 8 8608 R-MMU-5620912 Anchoring of the basal body to the plasma membrane 1.00000000000486 4.86418525205092e-12 93 0 0 8 8608 R-MMU-156827 L13a-mediated translational silencing of Ceruloplasmin expression 1.00000000000486 4.86418525205092e-12 93 0 0 8 8608 R-MMU-5693571 Nonhomologous End-Joining (NHEJ) 1.00000000000495 4.94786371880528e-12 48 0 0 8 8608 R-MMU-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 1.00000000000495 4.94786371880528e-12 48 0 0 8 8608 R-MMU-189200 Hexose transport 1.00000000000495 4.94786371880528e-12 48 0 0 8 8608 R-MMU-114604 GPVI-mediated activation cascade 1.00000000000495 4.94786371880528e-12 48 0 0 8 8608 R-MMU-445717 Aquaporin-mediated transport 1.00000000000495 4.94786371880528e-12 48 0 0 8 8608 R-MMU-1592389 Activation of Matrix Metalloproteinases 1.00000000000495 4.94786371880528e-12 48 0 0 8 8608 R-MMU-6794362 Protein-protein interactions at synapses 1.00000000000495 4.94786371880528e-12 48 0 0 8 8608 R-MMU-69620 Cell Cycle Checkpoints 1.00000000000516 5.16213395441746e-12 178 0 0 8 8608 R-MMU-196071 Metabolism of steroid hormones 1.00000000000528 5.28108601649986e-12 36 0 0 8 8608 R-MMU-76046 RNA Polymerase III Transcription Initiation 1.00000000000528 5.28108601649986e-12 36 0 0 8 8608 R-MMU-74158 RNA Polymerase III Transcription 1.00000000000528 5.28108601649986e-12 36 0 0 8 8608 R-MMU-427359 SIRT1 negatively regulates rRNA Expression 1.00000000000528 5.28108601649986e-12 36 0 0 8 8608 R-MMU-948021 Transport to the Golgi and subsequent modification 1.00000000000536 5.36355626554397e-12 146 0 0 8 8608 R-MMU-202424 Downstream TCR signaling 1.00000000000542 5.42475198655409e-12 88 0 0 8 8608 R-MMU-166520 Signalling by NGF 1.00000000000544 5.44339552235243e-12 407 0 0 8 8608 R-MMU-194306 Neurophilin interactions with VEGF and VEGFR 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-6807062 Cholesterol biosynthesis via lathosterol 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-888593 Reuptake of GABA 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-419771 Opsins 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-156842 Eukaryotic Translation Elongation 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-399710 Activation of AMPA receptors 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-6783984 Glycine degradation 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-5621480 Dectin-2 family 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-209563 Axonal growth stimulation 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-69200 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-392851 Prostacyclin signalling through prostacyclin receptor 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-5660526 Response to metal ions 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-4551638 SUMOylation of chromatin organization proteins 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-111932 CaMK IV-mediated phosphorylation of CREB 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-6803544 Ion influx/efflux at host-pathogen interface 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-5661231 Metallothioneins bind metals 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-804914 Transport of fatty acids 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-1855191 Synthesis of IPs in the nucleus 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-2142789 Ubiquinol biosynthesis 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-3000484 Scavenging by Class F Receptors 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-426486 Small interfering RNA (siRNA) biogenesis 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-444209 Free fatty acid receptors 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-8849474 PTK6 Activates STAT3 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-5221030 TET1,2,3 and TDG demethylate DNA 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-2243919 Crosslinking of collagen fibrils 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-442745 Activation of CaMK IV 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-3000497 Scavenging by Class H Receptors 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-1614517 Sulfide oxidation to sulfate 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-1989781 PPARA activates gene expression 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-210455 Astrocytic Glutamate-Glutamine Uptake And Metabolism 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-427975 Proton/oligopeptide cotransporters 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-8848584 Wax biosynthesis 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-190861 Gap junction assembly 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-110381 Resolution of AP sites via the single-nucleotide replacement pathway 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-209905 Catecholamine biosynthesis 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-5610783 Degradation of GLI2 by the proteasome 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-77352 Beta oxidation of butanoyl-CoA to acetyl-CoA 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-561048 Organic anion transport 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-390650 Histamine receptors 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-165158 Activation of AKT2 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-8849470 PTK6 Regulates Cell Cycle 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-1296053 Classical Kir channels 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-204626 Hypusine synthesis from eIF5A-lysine 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-844455 The NLRP1 inflammasome 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-381033 ATF6 (ATF6-alpha) activates chaperones 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-140179 Amine Oxidase reactions 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-447115 Interleukin-12 signaling 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-6807047 Cholesterol biosynthesis via desmosterol 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-1296061 HCN channels 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-1296025 ATP sensitive Potassium channels 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-71262 Carnitine synthesis 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-209931 Serotonin and melatonin biosynthesis 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-8853383 Lysosomal oligosaccharide catabolism 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-75072 mRNA Editing 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-176974 Unwinding of DNA 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-2142850 Hyaluronan biosynthesis and export 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-112313 Neurotransmitter uptake and Metabolism In Glial Cells 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-2473224 Antagonism of Activin by Follistatin 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-6799990 Metal sequestration by antimicrobial proteins 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-8866910 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-1237112 Methionine salvage pathway 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-3000471 Scavenging by Class B Receptors 1.00000000000564 5.63734670101174e-12 4 0 0 8 8608 R-MMU-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 1.00000000000566 5.65670047200668e-12 138 0 0 8 8608 R-MMU-167044 Signalling to RAS 1.00000000000574 5.74375724771937e-12 218 0 0 8 8608 R-MMU-170968 Frs2-mediated activation 1.00000000000574 5.74375724771937e-12 218 0 0 8 8608 R-MMU-5684996 MAPK1/MAPK3 signaling 1.00000000000574 5.74375724771937e-12 218 0 0 8 8608 R-MMU-170984 ARMS-mediated activation 1.00000000000574 5.74375724771937e-12 218 0 0 8 8608 R-MMU-2172127 DAP12 interactions 1.00000000000576 5.75641994892856e-12 316 0 0 8 8608 R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis 1.00000000000589 5.8899682094814e-12 85 0 0 8 8608 R-MMU-5419276 Mitochondrial translation termination 1.00000000000589 5.8899682094814e-12 85 0 0 8 8608 R-MMU-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 1.00000000000589 5.8899682094814e-12 85 0 0 8 8608 R-MMU-186763 Downstream signal transduction 1.00000000000601 6.00922349260081e-12 301 0 0 8 8608 R-MMU-1234174 Regulation of Hypoxia-inducible Factor (HIF) by oxygen 1.00000000000611 6.10696514553628e-12 68 0 0 8 8608 R-MMU-174824 Lipoprotein metabolism 1.00000000000611 6.10696514553628e-12 68 0 0 8 8608 R-MMU-2262749 Cellular response to hypoxia 1.00000000000611 6.10696514553628e-12 68 0 0 8 8608 R-MMU-2395516 Electron transport from NADPH to Ferredoxin 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-350864 Regulation of thyroid hormone activity 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-139910 Activation of BMF and translocation to mitochondria 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-1299308 Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-177135 Conjugation of benzoate with glycine 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-964975 Vitamins B6 activation to pyridoxal phosphate 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-5624958 ARL13B-mediated ciliary trafficking of INPP5E 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-5653890 Lactose synthesis 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-2465910 MASTL Facilitates Mitotic Progression 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-191647 c-src mediated regulation of Cx43 function and closure of gap junctions 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-165181 Inhibition of TSC complex formation by PKB 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-111458 Formation of apoptosome 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-113507 E2F-enabled inhibition of pre-replication complex formation 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-173599 Formation of the active cofactor, UDP-glucuronate 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-1296067 Potassium transport channels 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-3249367 STAT6-mediated induction of chemokines 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-446205 Synthesis of GDP-mannose 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-8849472 PTK6 Down-Regulation 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-110331 Cleavage of the damaged purine 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-265473 Trafficking of dietary sterols 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-77305 Beta oxidation of palmitoyl-CoA to myristoyl-CoA 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-159424 Conjugation of carboxylic acids 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-2993913 Clearance of Nuclear Envelope Membranes from Chromatin 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-162699 Synthesis of dolichyl-phosphate mannose 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-1307965 betaKlotho-mediated ligand binding 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-191650 Regulation of gap junction activity 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-156587 Amino Acid conjugation 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-156582 Acetylation 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-5667092 Nr1d1 (Rev-erba) represses gene expression 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-5627083 RHO GTPases regulate CFTR trafficking 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-77108 Utilization of Ketone Bodies 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-2408508 Metabolism of ingested SeMet, Sec, MeSec into H2Se 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-351200 Interconversion of polyamines 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-111469 SMAC-mediated apoptotic response 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-2161541 Abacavir metabolism 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-77285 Beta oxidation of myristoyl-CoA to lauroyl-CoA 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-352238 Breakdown of the nuclear lamina 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-427589 Type II Na+/Pi cotransporters 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-8847453 Synthesis of PIPs in the nucleus 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-418890 Role of second messengers in netrin-1 signaling 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-444411 Rhesus glycoproteins mediate ammonium transport. 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-111463 SMAC binds to IAPs 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-380615 Serotonin clearance from the synaptic cleft 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-217271 FMO oxidises nucleophiles 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-880009 Interconversion of 2-oxoglutarate and 2-hydroxyglutarate 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-379401 Dopamine clearance from the synaptic cleft 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-111446 Activation of BIM and translocation to mitochondria 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-163282 Mitochondrial transcription initiation 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-3065676 SUMO is conjugated to E1 (UBA2:SAE1) 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-8866911 TFAP2 (AP-2) family regulates transcription of cell cycle factors 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-1234162 Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-977442 GABA A (rho) receptor activation 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-73927 Depurination 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-190374 FGFR1c and Klotho ligand binding and activation 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-964827 Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-1483248 Synthesis of PIPs at the ER membrane 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-429593 Inositol transporters 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-1299503 TWIK related potassium channel (TREK) 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-1606341 IRF3 mediated activation of type 1 IFN 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-844615 The AIM2 inflammasome 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-428542 Regulation of Commissural axon pathfinding by Slit and Robo 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-173736 Alternative complement activation 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-1368071 NR1D1 (REV-ERBA) represses gene expression 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-111464 SMAC-mediated dissociation of IAP:caspase complexes 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-428776 Class II GLUTs 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-8875791 MET activates STAT3 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-428808 Na+-dependent glucose transporters 1.00000000000625 6.25187692429387e-12 3 0 0 8 8608 R-MMU-112315 Transmission across Chemical Synapses 1.0000000000068 6.80231285635992e-12 196 0 0 8 8608 R-MMU-2424491 DAP12 signaling 1.00000000000697 6.97393433243961e-12 307 0 0 8 8608 R-MMU-2871796 FCERI mediated MAPK activation 1.00000000000712 7.11874905072753e-12 233 0 0 8 8608 R-MMU-2559586 DNA Damage/Telomere Stress Induced Senescence 1.0000000000073 7.29999946850276e-12 44 0 0 8 8608 R-MMU-913709 O-linked glycosylation of mucins 1.0000000000073 7.29999946850276e-12 44 0 0 8 8608 R-MMU-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 1.0000000000073 7.29999946850276e-12 44 0 0 8 8608 R-MMU-2173782 Binding and Uptake of Ligands by Scavenger Receptors 1.0000000000073 7.29999946850276e-12 44 0 0 8 8608 R-MMU-194068 Bile acid and bile salt metabolism 1.0000000000073 7.29999946850276e-12 44 0 0 8 8608 R-MMU-75953 RNA Polymerase II Transcription Initiation 1.0000000000073 7.29999946850276e-12 44 0 0 8 8608 R-MMU-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 1.0000000000073 7.29999946850276e-12 44 0 0 8 8608 R-MMU-4615885 SUMOylation of DNA replication proteins 1.0000000000073 7.29999946850276e-12 44 0 0 8 8608 R-MMU-73776 RNA Polymerase II Promoter Escape 1.0000000000073 7.29999946850276e-12 44 0 0 8 8608 R-MMU-1474244 Extracellular matrix organization 1.00000000000735 7.3513656228536e-12 270 0 0 8 8608 R-MMU-983169 Class I MHC mediated antigen processing & presentation 1.00000000000743 7.42901542364775e-12 212 0 0 8 8608 R-MMU-5683057 MAPK family signaling cascades 1.00000000000761 7.61313122917316e-12 243 0 0 8 8608 R-MMU-68962 Activation of the pre-replicative complex 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-508751 Circadian Clock 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-5654687 Downstream signaling of activated FGFR1 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-6791312 TP53 Regulates Transcription of Cell Cycle Genes 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-2514856 The phototransduction cascade 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-1170546 Prolactin receptor signaling 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-73933 Resolution of Abasic Sites (AP sites) 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-8854214 TBC/RABGAPs 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-73863 RNA Polymerase I Transcription Termination 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-390522 Striated Muscle Contraction 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-6806003 Regulation of TP53 Expression and Degradation 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-73728 RNA Polymerase I Promoter Opening 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-5663213 RHO GTPases Activate WASPs and WAVEs 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-5654726 Negative regulation of FGFR1 signaling 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-6804757 Regulation of TP53 Degradation 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-1296065 Inwardly rectifying K+ channels 1.00000000000773 7.72987799298522e-12 31 0 0 8 8608 R-MMU-187037 NGF signalling via TRKA from the plasma membrane 1.00000000000818 8.17510264093225e-12 321 0 0 8 8608 R-MMU-500792 GPCR ligand binding 1.00000000000818 8.17673656215361e-12 401 0 0 8 8608 R-MMU-112314 Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell 1.00000000000828 8.28293078589698e-12 135 0 0 8 8608 R-MMU-5358351 Signaling by Hedgehog 1.00000000000828 8.28293078589698e-12 135 0 0 8 8608 R-MMU-72172 mRNA Splicing 1.00000000000829 8.28653939972672e-12 177 0 0 8 8608 R-MMU-186797 Signaling by PDGF 1.00000000000846 8.46112328100623e-12 322 0 0 8 8608 R-MMU-5683826 Surfactant metabolism 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-3295583 TRP channels 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-975576 N-glycan antennae elongation in the medial/trans-Golgi 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-2168880 Scavenging of heme from plasma 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-174800 Chylomicron-mediated lipid transport 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-110314 Recognition of DNA damage by PCNA-containing replication complex 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-1296041 Activation of G protein gated Potassium channels 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-1538133 G0 and Early G1 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-3928663 EPHA-mediated growth cone collapse 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-70614 Amino acid synthesis and interconversion (transamination) 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-5654708 Downstream signaling of activated FGFR3 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-1296059 G protein gated Potassium channels 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-901042 Calnexin/calreticulin cycle 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-5654700 FRS-mediated FGFR2 signaling 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-191273 Cholesterol biosynthesis 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-389661 Glyoxylate metabolism and glycine degradation 1.00000000000849 8.4913216555125e-12 25 0 0 8 8608 R-MMU-194315 Signaling by Rho GTPases 1.00000000000855 8.55376749319164e-12 362 0 0 8 8608 R-MMU-2029482 Regulation of actin dynamics for phagocytic cup formation 1.00000000000859 8.59210631853842e-12 46 0 0 8 8608 R-MMU-1660499 Synthesis of PIPs at the plasma membrane 1.00000000000859 8.59210631853842e-12 46 0 0 8 8608 R-MMU-112310 Neurotransmitter Release Cycle 1.00000000000859 8.59210631853842e-12 46 0 0 8 8608 R-MMU-5628897 TP53 Regulates Metabolic Genes 1.00000000000859 8.59210631853842e-12 46 0 0 8 8608 R-MMU-71406 Pyruvate metabolism and Citric Acid (TCA) cycle 1.00000000000859 8.59210631853842e-12 46 0 0 8 8608 R-MMU-73762 RNA Polymerase I Transcription Initiation 1.00000000000859 8.59210631853842e-12 46 0 0 8 8608 R-MMU-446388 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-156711 Polo-like kinase mediated events 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-447038 NrCAM interactions 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-1483226 Synthesis of PI 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-2161517 Abacavir transmembrane transport 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-390651 Dopamine receptors 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-8875513 MET interacts with TNS proteins 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-2142700 Synthesis of Lipoxins (LX) 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-442720 CREB phosphorylation through the activation of Adenylate Cyclase 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-1169092 Activation of RAS in B cells 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-937072 TRAF6 mediated induction of TAK1 complex 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-5662702 Melanin biosynthesis 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-203641 NOSTRIN mediated eNOS trafficking 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-418217 G beta:gamma signalling through PLC beta 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-8865999 MET activates PTPN11 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-140834 Extrinsic Pathway of Fibrin Clot Formation 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-977347 Serine biosynthesis 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-380095 Tachykinin receptors bind tachykinins 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-418886 Netrin mediated repulsion signals 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-5624138 Trafficking of myristoylated proteins to the cilium 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-2187335 The retinoid cycle in cones (daylight vision) 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-1482798 Acyl chain remodeling of CL 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-390648 Muscarinic acetylcholine receptors 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-5576890 Phase 3 - rapid repolarisation 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-5362798 Release of Hh-Np from the secreting cell 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-70370 Galactose catabolism 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-77348 Beta oxidation of octanoyl-CoA to hexanoyl-CoA 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-71032 Propionyl-CoA catabolism 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-112307 Transmission across Electrical Synapses 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-389599 Alpha-oxidation of phytanate 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-8866423 VLDL biosynthesis 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-1566977 Fibronectin matrix formation 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-112303 Electric Transmission Across Gap Junctions 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-3065678 SUMO is transferred from E1 to E2 (UBE2I, UBC9) 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-8866376 Reelin signalling pathway 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-77346 Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-1912399 Pre-NOTCH Processing in the Endoplasmic Reticulum 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-196819 Vitamin B1 (thiamin) metabolism 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-167827 The proton buffering model 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-427652 Sodium-coupled phosphate cotransporters 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-964739 N-glycan trimming and elongation in the cis-Golgi 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-69478 G2/M DNA replication checkpoint 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-426048 Arachidonate production from DAG 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-77350 Beta oxidation of hexanoyl-CoA to butanoyl-CoA 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-433137 Sodium-coupled sulphate, di- and tri-carboxylate transporters 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-75205 Dissolution of Fibrin Clot 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-75944 Transcription from mitochondrial promoters 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-166187 Mitochondrial Uncoupling Proteins 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-210746 Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-111459 Activation of caspases through apoptosome-mediated cleavage 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-8849468 PTK6 Regulates Proteins Involved in RNA Processing 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-400511 Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-167826 The fatty acid cycling model 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-5578768 Physiological factors 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-111461 Cytochrome c-mediated apoptotic response 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-1433617 Regulation of signaling by NODAL 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-2142712 Synthesis of 12-eicosatetraenoic acid derivatives 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-77310 Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-417973 Adenosine P1 receptors 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-5627117 RHO GTPases Activate ROCKs 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-5661270 Catabolism of glucuronate to xylulose-5-phosphate 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-174577 Activation of C3 and C5 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-391906 Leukotriene receptors 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-68911 G2 Phase 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-918233 TRAF3-dependent IRF activation pathway 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-1306955 GRB7 events in ERBB2 signaling 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-114516 Disinhibition of SNARE formation 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-428890 Role of Abl in Robo-Slit signaling 1.0000000000092 9.20284159585829e-12 5 0 0 8 8608 R-MMU-451927 Interleukin-2 signaling 1.00000000000981 9.80749319905214e-12 228 0 0 8 8608 R-MMU-72203 Processing of Capped Intron-Containing Pre-mRNA 1.00000000000981 9.80749319905214e-12 228 0 0 8 8608 R-MMU-202403 TCR signaling 1.0000000000103 1.02965783906874e-11 108 0 0 8 8608 R-MMU-199991 Membrane Trafficking 1.00000000001037 1.03679734512468e-11 497 0 0 8 8608 R-MMU-389887 Beta-oxidation of pristanoyl-CoA 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-450341 Activation of the AP-1 family of transcription factors 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-399997 Acetylcholine regulates insulin secretion 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-74749 Signal attenuation 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-5173214 O-glycosylation of TSR domain-containing proteins 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-1912420 Pre-NOTCH Processing in Golgi 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-209968 Thyroxine biosynthesis 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-111367 SLBP independent Processing of Histone Pre-mRNAs 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-2022857 Keratan sulfate degradation 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-1358803 Downregulation of ERBB2:ERBB3 signaling 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-1059683 Interleukin-6 signaling 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-3371568 Attenuation phase 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-418592 ADP signalling through P2Y purinoceptor 1 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-844456 The NLRP3 inflammasome 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-373753 Nephrin interactions 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-419408 Lysosphingolipid and LPA receptors 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-192456 Digestion of dietary lipid 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-2470946 Cohesin Loading onto Chromatin 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-418889 Ligand-independent caspase activation via DCC 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-3215018 Processing and activation of SUMO 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-8854691 Interleukin-19, 20, 22, 24 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-1855167 Synthesis of pyrophosphates in the cytosol 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-170660 Adenylate cyclase activating pathway 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-5666185 RHO GTPases Activate Rhotekin and Rhophilins 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-428643 Organic anion transporters 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-420029 Tight junction interactions 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-2197563 NOTCH2 intracellular domain regulates transcription 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-71336 Pentose phosphate pathway (hexose monophosphate shunt) 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-432047 Passive transport by Aquaporins 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-425381 Bicarbonate transporters 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-1834941 STING mediated induction of host immune responses 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-5625900 RHO GTPases activate CIT 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-73614 Pyrimidine salvage reactions 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-430116 GP1b-IX-V activation signalling 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-156588 Glucuronidation 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-419812 Calcitonin-like ligand receptors 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-5620922 BBSome-mediated cargo-targeting to cilium 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-1300642 Sperm Motility And Taxes 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-112308 Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-73929 Base-Excision Repair, AP Site Formation 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-174437 Removal of the Flap Intermediate from the C-strand 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-1660517 Synthesis of PIPs at the late endosome membrane 1.0000000000104 1.0400936242724e-11 10 0 0 8 8608 R-MMU-2454202 Fc epsilon receptor (FCERI) signaling 1.00000000001051 1.05136033378956e-11 317 0 0 8 8608 R-MMU-112399 IRS-mediated signalling 1.00000000001072 1.07162702718602e-11 262 0 0 8 8608 R-MMU-73886 Chromosome Maintenance 1.00000000001085 1.08547242836007e-11 67 0 0 8 8608 R-MMU-373760 L1CAM interactions 1.00000000001085 1.08547242836007e-11 67 0 0 8 8608 R-MMU-68867 Assembly of the pre-replicative complex 1.00000000001085 1.08547242836007e-11 67 0 0 8 8608 R-MMU-380284 Loss of proteins required for interphase microtubule organization from the centrosome 1.00000000001085 1.08547242836007e-11 67 0 0 8 8608 R-MMU-380259 Loss of Nlp from mitotic centrosomes 1.00000000001085 1.08547242836007e-11 67 0 0 8 8608 R-MMU-6811440 Retrograde transport at the Trans-Golgi-Network 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-112040 G-protein mediated events 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-211981 Xenobiotics 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-774815 Nucleosome assembly 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-1236394 Signaling by ERBB4 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-446652 Interleukin-1 signaling 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-606279 Deposition of new CENPA-containing nucleosomes at the centromere 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-212300 PRC2 methylates histones and DNA 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-8948216 Collagen chain trimerization 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-982772 Growth hormone receptor signaling 1.00000000001087 1.08745361870712e-11 41 0 0 8 8608 R-MMU-72163 mRNA Splicing - Major Pathway 1.00000000001122 1.12167171170759e-11 168 0 0 8 8608 R-MMU-5617833 Cilium Assembly 1.00000000001122 1.12167171170759e-11 168 0 0 8 8608 R-MMU-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 1.00000000001125 1.12485314616399e-11 35 0 0 8 8608 R-MMU-5696400 Dual Incision in GG-NER 1.00000000001125 1.12485314616399e-11 35 0 0 8 8608 R-MMU-3299685 Detoxification of Reactive Oxygen Species 1.00000000001125 1.12485314616399e-11 35 0 0 8 8608 R-MMU-375280 Amine ligand-binding receptors 1.00000000001125 1.12485314616399e-11 35 0 0 8 8608 R-MMU-432720 Lysosome Vesicle Biogenesis 1.00000000001125 1.12485314616399e-11 35 0 0 8 8608 R-MMU-73847 Purine metabolism 1.00000000001125 1.12485314616399e-11 35 0 0 8 8608 R-MMU-418990 Adherens junctions interactions 1.00000000001125 1.12485314616399e-11 35 0 0 8 8608 R-MMU-2559583 Cellular Senescence 1.00000000001159 1.15899479072701e-11 137 0 0 8 8608 R-MMU-901032 ER Quality Control Compartment (ERQC) 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-171052 LDL-mediated lipid transport 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-2024096 HS-GAG degradation 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-71403 Citric acid cycle (TCA cycle) 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-2022870 Chondroitin sulfate biosynthesis 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-69186 Lagging Strand Synthesis 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-8849932 SALM protein interactions at the synapses 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-198753 ERK/MAPK targets 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-389513 CTLA4 inhibitory signaling 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-5654719 SHC-mediated cascade:FGFR4 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-5654720 PI-3K cascade:FGFR4 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-2028269 Signaling by Hippo 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-983189 Kinesins 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-5654706 FRS-mediated FGFR3 signaling 1.00000000001188 1.1877868491282e-11 20 0 0 8 8608 R-MMU-512988 Interleukin-3, 5 and GM-CSF signaling 1.00000000001211 1.21119378021974e-11 232 0 0 8 8608 R-MMU-8853659 RET signaling 1.00000000001211 1.21119378021974e-11 232 0 0 8 8608 R-MMU-71291 Metabolism of amino acids and derivatives 1.00000000001211 1.21119378021974e-11 232 0 0 8 8608 R-MMU-194138 Signaling by VEGF 1.00000000001227 1.22673911833067e-11 295 0 0 8 8608 R-MMU-1168372 Downstream signaling events of B Cell Receptor (BCR) 1.00000000001253 1.25261475436628e-11 179 0 0 8 8608 R-MMU-69002 DNA Replication Pre-Initiation 1.00000000001263 1.26334203864881e-11 83 0 0 8 8608 R-MMU-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 1.00000000001263 1.26334203864881e-11 83 0 0 8 8608 R-MMU-68874 M/G1 Transition 1.00000000001263 1.26334203864881e-11 83 0 0 8 8608 R-MMU-168138 Toll Like Receptor 9 (TLR9) Cascade 1.00000000001263 1.26334203864881e-11 83 0 0 8 8608 R-MMU-190236 Signaling by FGFR 1.00000000001263 1.26334203864881e-11 83 0 0 8 8608 R-MMU-5389840 Mitochondrial translation elongation 1.00000000001263 1.26334203864881e-11 83 0 0 8 8608 R-MMU-68949 Orc1 removal from chromatin 1.00000000001301 1.30144775140062e-11 70 0 0 8 8608 R-MMU-69052 Switching of origins to a post-replicative state 1.00000000001301 1.30144775140062e-11 70 0 0 8 8608 R-MMU-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 1.00000000001301 1.30144775140062e-11 70 0 0 8 8608 R-MMU-8854518 AURKA Activation by TPX2 1.00000000001301 1.30144775140062e-11 70 0 0 8 8608 R-MMU-5654738 Signaling by FGFR2 1.00000000001301 1.30144775140062e-11 70 0 0 8 8608 R-MMU-1660514 Synthesis of PIPs at the Golgi membrane 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-450604 KSRP (KHSRP) binds and destabilizes mRNA 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-5423646 Aflatoxin activation and detoxification 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-1606322 ZBP1(DAI) mediated induction of type I IFNs 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-392518 Signal amplification 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-438066 Unblocking of NMDA receptor, glutamate binding and activation 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-400685 Sema4D in semaphorin signaling 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-196757 Metabolism of folate and pterines 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-6804760 Regulation of TP53 Activity through Methylation 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-209776 Amine-derived hormones 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-3928664 Ephrin signaling 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-451326 Activation of Kainate Receptors upon glutamate binding 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-456926 Thrombin signalling through proteinase activated receptors (PARs) 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-442729 CREB phosphorylation through the activation of CaMKII 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-1482925 Acyl chain remodelling of PG 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-5651801 PCNA-Dependent Long Patch Base Excision Repair 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-877300 Interferon gamma signaling 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 1.00000000001329 1.32859537581303e-11 17 0 0 8 8608 R-MMU-2586552 Signaling by Leptin 1.0000000000133 1.3297423910813e-11 221 0 0 8 8608 R-MMU-169893 Prolonged ERK activation events 1.0000000000133 1.3297423910813e-11 221 0 0 8 8608 R-MMU-912526 Interleukin receptor SHC signaling 1.0000000000133 1.3297423910813e-11 221 0 0 8 8608 R-MMU-211859 Biological oxidations 1.00000000001355 1.35464633607616e-11 230 0 0 8 8608 R-MMU-196849 Metabolism of water-soluble vitamins and cofactors 1.00000000001363 1.36257555399141e-11 112 0 0 8 8608 R-MMU-5663220 RHO GTPases Activate Formins 1.00000000001363 1.36257555399141e-11 112 0 0 8 8608 R-MMU-2132295 MHC class II antigen presentation 1.00000000001364 1.36402135284172e-11 94 0 0 8 8608 R-MMU-5689603 UCH proteinases 1.00000000001364 1.36402135284172e-11 94 0 0 8 8608 R-MMU-2187338 Visual phototransduction 1.00000000001385 1.38484960570237e-11 87 0 0 8 8608 R-MMU-2555396 Mitotic Metaphase and Anaphase 1.00000000001433 1.43318017351973e-11 172 0 0 8 8608 R-MMU-71387 Metabolism of carbohydrates 1.00000000001455 1.45476682781704e-11 271 0 0 8 8608 R-MMU-159740 Gamma-carboxylation of protein precursors 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-912631 Regulation of signaling by CBL 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-1855183 Synthesis of IP2, IP, and Ins in the cytosol 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-417957 P2Y receptors 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-68689 CDC6 association with the ORC:origin complex 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-159763 Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-199220 Vitamin B5 (pantothenate) metabolism 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-8851805 MET activates RAS signaling 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-629594 Highly calcium permeable postsynaptic nicotinic acetylcholine receptors 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-391160 Signal regulatory protein (SIRP) family interactions 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-190373 FGFR1c ligand binding and activation 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-177504 Retrograde neurotrophin signalling 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-390666 Serotonin receptors 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-74259 Purine catabolism 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-2468052 Establishment of Sister Chromatid Cohesion 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-200425 Import of palmitoyl-CoA into the mitochondrial matrix 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-350054 Notch-HLH transcription pathway 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-190828 Gap junction trafficking 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-73621 Pyrimidine catabolism 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-3134963 DEx/H-box helicases activate type I IFN and inflammatory cytokines production 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-174414 Processive synthesis on the C-strand of the telomere 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-380320 Recruitment of NuMA to mitotic centrosomes 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-1368092 Rora activates gene expression 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-189451 Heme biosynthesis 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-381771 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-193692 Regulated proteolysis of p75NTR 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-376172 DSCAM interactions 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-444473 Formyl peptide receptors bind formyl peptides and many other ligands 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-2160916 Hyaluronan uptake and degradation 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-418885 DCC mediated attractive signaling 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-209952 Peptide hormone biosynthesis 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-8875555 MET activates RAP1 and RAC1 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-1296346 Tandem pore domain potassium channels 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-375281 Hormone ligand-binding receptors 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-196780 Biotin transport and metabolism 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-2586551 Signaling by Leptin 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-203615 eNOS activation 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-71240 Tryptophan catabolism 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-2022923 Dermatan sulfate biosynthesis 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-71384 Ethanol oxidation 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-8851680 Butyrophilin (BTN) family interactions 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-549127 Organic cation transport 1.0000000000147 1.46963264764846e-11 11 0 0 8 8608 R-MMU-212165 Epigenetic regulation of gene expression 1.0000000000153 1.53019098874965e-11 133 0 0 8 8608 R-MMU-5693532 DNA Double-Strand Break Repair 1.0000000000153 1.53019098874965e-11 133 0 0 8 8608 R-MMU-425393 Transport of inorganic cations/anions and amino acids/oligopeptides 1.00000000001561 1.56109868463009e-11 106 0 0 8 8608 R-MMU-69306 DNA Replication 1.00000000001561 1.56109868463009e-11 106 0 0 8 8608 R-MMU-69615 G1/S DNA Damage Checkpoints 1.00000000001569 1.56858157766228e-11 64 0 0 8 8608 R-MMU-73856 RNA Polymerase II Transcription Termination 1.00000000001569 1.56858157766228e-11 64 0 0 8 8608 R-MMU-611105 Respiratory electron transport 1.00000000001569 1.56858157766228e-11 64 0 0 8 8608 R-MMU-109688 Cleavage of Growing Transcript in the Termination Region 1.00000000001569 1.56858157766228e-11 64 0 0 8 8608 R-MMU-5173105 O-linked glycosylation 1.00000000001569 1.56858157766228e-11 64 0 0 8 8608 R-MMU-446219 Synthesis of substrates in N-glycan biosythesis 1.00000000001572 1.57208044249077e-11 60 0 0 8 8608 R-MMU-204005 COPII (Coat Protein 2) Mediated Vesicle Transport 1.00000000001572 1.57208044249077e-11 60 0 0 8 8608 R-MMU-5685942 HDR through Homologous Recombination (HRR) 1.00000000001572 1.57208044249077e-11 60 0 0 8 8608 R-MMU-1280218 Adaptive Immune System 1.00000000001586 1.58606693178929e-11 594 0 0 8 8608 R-MMU-69278 Cell Cycle, Mitotic 1.00000000001623 1.62257706033188e-11 435 0 0 8 8608 R-MMU-164378 PKA activation in glucagon signalling 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-3134975 Regulation of innate immune responses to cytosolic DNA 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-389948 PD-1 signaling 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-5656121 Translesion synthesis by POLI 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-205043 NRIF signals cell death from the nucleus 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-416993 Trafficking of GluR2-containing AMPA receptors 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-2029485 Role of phospholipids in phagocytosis 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-1980145 Signaling by NOTCH2 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-5655862 Translesion synthesis by POLK 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-2453902 The canonical retinoid cycle in rods (twilight vision) 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-429958 mRNA decay by 3' to 5' exoribonuclease 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-264642 Acetylcholine Neurotransmitter Release Cycle 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-5686938 Regulation of TLR by endogenous ligand 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-1482922 Acyl chain remodelling of PI 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-5654219 Phospholipase C-mediated cascade: FGFR1 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-933542 TRAF6 mediated NF-kB activation 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-622312 Inflammasomes 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-4641263 Regulation of FZD by ubiquitination 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-392154 Nitric oxide stimulates guanylate cyclase 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-163210 Formation of ATP by chemiosmotic coupling 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-8876725 Protein methylation 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-166663 Initial triggering of complement 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-418038 Nucleotide-like (purinergic) receptors 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-69205 G1/S-Specific Transcription 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-112409 RAF-independent MAPK1/3 activation 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-422085 Synthesis, secretion, and deacylation of Ghrelin 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-181430 Norepinephrine Neurotransmitter Release Cycle 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-399956 CRMPs in Sema3A signaling 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-936440 Negative regulators of RIG-I/MDA5 signaling 1.0000000000171 1.70966172757809e-11 16 0 0 8 8608 R-MMU-1474228 Degradation of the extracellular matrix 1.00000000001764 1.76420241607134e-11 107 0 0 8 8608 R-MMU-3858494 Beta-catenin independent WNT signaling 1.00000000001764 1.76420241607134e-11 107 0 0 8 8608 R-MMU-4086400 PCP/CE pathway 1.00000000001841 1.84146143261288e-11 81 0 0 8 8608 R-MMU-937061 TRIF-mediated TLR3/TLR4 signaling 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-2682334 EPH-Ephrin signaling 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-72202 Transport of Mature Transcript to Cytoplasm 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-70326 Glucose metabolism 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-75109 Triglyceride Biosynthesis 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-1483255 PI Metabolism 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-6807878 COPI-mediated anterograde transport 1.00000000001881 1.88080698461132e-11 71 0 0 8 8608 R-MMU-375165 NCAM signaling for neurite out-growth 1.00000000001892 1.89187240713345e-11 237 0 0 8 8608 R-MMU-76009 Platelet Aggregation (Plug Formation) 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-5689901 Metalloprotease DUBs 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-438064 Post NMDA receptor activation events 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-69236 G1 Phase 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-163841 Gamma carboxylation, hypusine formation and arylsulfatase activation 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-110313 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-5696394 DNA Damage Recognition in GG-NER 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-5675221 Negative regulation of MAPK pathway 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-69231 Cyclin D associated events in G1 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-1483166 Synthesis of PA 1.00000000001904 1.90385337852256e-11 34 0 0 8 8608 R-MMU-1442490 Collagen degradation 1.0000000000193 1.92981485919936e-11 47 0 0 8 8608 R-MMU-72695 Formation of the ternary complex, and subsequently, the 43S complex 1.0000000000193 1.92981485919936e-11 47 0 0 8 8608 R-MMU-5654736 Signaling by FGFR1 1.0000000000193 1.92981485919936e-11 47 0 0 8 8608 R-MMU-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 1.0000000000193 1.92981485919936e-11 47 0 0 8 8608 R-MMU-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 1.0000000000193 1.92981485919936e-11 47 0 0 8 8608 R-MMU-1483249 Inositol phosphate metabolism 1.0000000000193 1.92981485919936e-11 47 0 0 8 8608 R-MMU-389356 CD28 co-stimulation 1.000000000021 2.10033517183082e-11 29 0 0 8 8608 R-MMU-392451 G beta:gamma signalling through PI3Kgamma 1.000000000021 2.10033517183082e-11 29 0 0 8 8608 R-MMU-450282 MAPK targets/ Nuclear events mediated by MAP kinases 1.000000000021 2.10033517183082e-11 29 0 0 8 8608 R-MMU-73777 RNA Polymerase I Chain Elongation 1.000000000021 2.10033517183082e-11 29 0 0 8 8608 R-MMU-5601884 PIWI-interacting RNA (piRNA) biogenesis 1.000000000021 2.10033517183082e-11 29 0 0 8 8608 R-MMU-8875878 MET promotes cell motility 1.000000000021 2.10033517183082e-11 29 0 0 8 8608 R-MMU-400253 Circadian Clock 1.000000000021 2.10033517183082e-11 29 0 0 8 8608 R-MMU-5365859 RA biosynthesis pathway 1.000000000021 2.10033517183082e-11 29 0 0 8 8608 R-MMU-6783589 Interleukin-6 family signaling 1.000000000021 2.10033517183082e-11 29 0 0 8 8608 R-MMU-72689 Formation of a pool of free 40S subunits 1.00000000002133 2.13265047520437e-11 84 0 0 8 8608 R-MMU-174143 APC/C-mediated degradation of cell cycle proteins 1.00000000002133 2.13265047520437e-11 84 0 0 8 8608 R-MMU-428157 Sphingolipid metabolism 1.00000000002133 2.13265047520437e-11 84 0 0 8 8608 R-MMU-453276 Regulation of mitotic cell cycle 1.00000000002133 2.13265047520437e-11 84 0 0 8 8608 R-MMU-193704 p75 NTR receptor-mediated signalling 1.00000000002133 2.13265047520437e-11 84 0 0 8 8608 R-MMU-2565942 Regulation of PLK1 Activity at G2/M Transition 1.00000000002133 2.13265047520437e-11 84 0 0 8 8608 R-MMU-2262752 Cellular responses to stress 1.00000000002208 2.2082614668273e-11 356 0 0 8 8608 R-MMU-380108 Chemokine receptors bind chemokines 1.00000000003892 3.89216963101373e-11 50 0 0 8 8608 R-MMU-3214842 HDMs demethylate histones 1.00000000003892 3.89216963101373e-11 50 0 0 8 8608 R-MMU-69017 CDK-mediated phosphorylation and removal of Cdc6 1.00000000003892 3.89216963101373e-11 50 0 0 8 8608 R-MMU-75105 Fatty Acyl-CoA Biosynthesis 1.00000000003892 3.89216963101373e-11 50 0 0 8 8608 R-MMU-5625740 RHO GTPases activate PKNs 1.00000000003892 3.89216963101373e-11 50 0 0 8 8608 R-MMU-6806667 Metabolism of fat-soluble vitamins 1.00000000003892 3.89216963101373e-11 50 0 0 8 8608