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Advanced Study Workshop

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Advanced Study Workshop The regulome: genome architecture and single cell transcriptomics

Organized by

Strategic Research Theme of Development & Reproduction
Strategic Research Theme of Genomics
Centre for Reproduction, Development & Growth
Centre for Genomic Sciences
Dr. Li Dak-Sum Research Centre
School of Biomedical Sciences, The University of Hong Kong

June 21 - 23, 2016 (Tuesday - Thursday)

 

Programme

Venues:  

  • HKJC – S3: Seminar Room 3, G/F, Hong Kong Jockey Club Building For Interdisciplinary Research, 5 Sassoon Road, Pokfulam, Hong Kong
  • CALLab: Computer Aided Learning Centre, LG1/F, William M.W. Mong Block, Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong
  • LT1: Cheung Kung Hai Lecture Theatre 1, William M.W. Mong Block, Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong
  • Alumni Chamber: 7/F, William M.W. Mong Block, Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong

 

Day 1 (21 June 2016, Tuesday)
Topic: Genome architecture & gene regulation I
Time Event Venue
08:30 – 08:45 Registration HKJC – S3
08:45 – 09:00 Opening address
Professor Pak Sham
Convener, Strategic Research Theme of Genomics; Director, Centre for Genomic Sciences, The University of Hong Kong, HK
HKJC – S3
Chairperson: Prof. Pak ShamResearch talks
09:00 – 10:00 Develop precision technologies for studying 3D cancer genomes
Professor Michael Zhang
Director, Center for Systems Biology, Department of Molecular & Cell Biology, The University of Texas at Dallas, USA
HKJC – S3
10:00 – 10:30 Tea break HKJC – S3
10:30 – 11:30 Quantitative modeling of transcriptional regulatory networks
Dr Kevin Yip
Department of Computer Science and Engineering, The Chinese University of Hong Kong, HK
HKJC – S3
11:30 – 12:30 The epigenome in mammalian development: non-coding DNA takes center stage
Dr Danny Leung
Division of Life Science, The Hong Kong University of Science and Technology, HK
HKJC – S3
12:30 End of morning session  
Chairperson: Dr Kevin YipConceptual teaching workshop
14:30 – 16:30 Bioinformatics aAnalysis of single-cell RNA-seq
Mr Yi Zhao
Institute of Computing Technology, Chinese Academy of Sciences, China
CALLab
16:30 – 17:00 Tea break LT1 Foyer
Chairperson: Prof. Danny ChanResearch talks
17:00 – 18:00 Pioneering chromatin for neural crest specification 
Dr Tatjana Sauka-Spengler
The Weatherall Institute of Molecular Medicine, University of Oxford, UK
LT1
18:00 – 19:00 Welcome mixer for workshop participants and speakers Alumni Chamber

 

Day 2 (22 June 2016, Wednesday)
Topic: Genome architecture & gene regulation II
Time Event Venue
08:45 – 09:00 Registration HKJC – S3
Chairperson: Prof. Kathryn CheahResearch talks
09:00 – 10:00 Single cell transcriptomics of neural crest cells reveals novel aspects of multiple fate selection
Dr Igor Adameyko
Department of Physiology and Pharmacology, Karolinska Institutet, Sweden
HKJC – S3
10:00 – 11:00 Exploring transcriptional and genetic intra-tumoral heterogeneity with single-cell data
Dr Peter V Kharchenko
Biomedical Informatics, Harvard Medical School, USA
HKJC – S3
11:00 – 11:30 Tea break HKJC – S3
Chairperson: Dr Bo GaoShort talks from participants
11:30 – 11:45 Identification of enhancers in notochordal lineage cells during intervertebral disc development
Dr Ray Ng
School of Biomedical Sciences, The University of Hong Kong
HKJC – S3
11:45 – 12:00 Transcriptional regulatory network of SoxE proteins in neural crest motility
Dr Martin Cheung
School of Biomedical Sciences, The University of Hong Kong
HKJC – S3
12:00 – 12:15 Reconstructing the chondro-osteoblastic lineage by single cell RNA-seq
Dr Kwok-Yeung Tsang
School of Biomedical Sciences, The University of Hong Kong
HKJC – S3
12:15 – 12:30 Exploring genetic associations with ceRNA regulation in the human genome
Dr Mulin Jun Li
Centre for Genomic Sciences, The University of Hong Kong
HKJC – S3
12:30 End of morning session  
Chairperson: Dr Miaoxin LiConceptual teaching workshop
14:30 – 16:30 Exploring transcriptional heterogeneity using PAGODA package
Dr Peter V Kharchenko
Biomedical Informatics, Harvard Medical School, USA
CALLab

 

Day 3 (23 June 2016, Thursday)
Topic: Genome architecture & gene regulation III
Time Event Venue
Chairperson: Dr Ray NgConceptual teaching workshop
09:00 – 11:00 Identification and characterisation of cis-regulatory circuits in specific cell populations in vivo using epigenomic and single cell approaches: technologies and challenges
Dr Tatjana Sauka-Spengler
The Weatherall Institute of Molecular Medicine, University of Oxford, UK
CALLab
11:00 – 11:30 Tea break LT1
Chairperson: Dr Ray NgResearch talks
11:30 – 12:30 Identification of causal DNA methylation events driving cancer progression
Dr Jiangwen Zhang
School of Biological Sciences, The University of Hong Kong, HK
LT1
12:30 – 14:00 Lunch (sandwiches will be provided for workshop participants)  
Facilitator: Dr Danny LeungTechnical clinic
Panelist: Speakers of the research talks
14:00 – 16:55 Technical clinic: question and answer session for workshop participants and speakers LT1
16:55 – 17:00 Closing remark
Professor Kathryn Cheah
Convener, Strategic Research Theme of Development & Reproduction, The University of Hong Kong, HK
LT1