Principal Investigators

Cheung, Lydia Wai Ting
Functional genomics for translational cancer medicine Cancer biology

Gao, Bo
Cell signaling in development and disease

He, Mu
Development and regeneration of the respiratory system Airway mucus and cilia interaction Airway organoid platforms for human disease modeling

Hervas Millan, Rubén
Biophysics and protein structure Protein aggregation in physiological processes Structure and activity of functional amyloids

Javed, Asif
Multi-omics analysis of cancers and rare diseases Computational biology

Kim, Jung
Systemic tumor-host interactions Paraneoplastic syndromes Tumor-dependent stem cell dysregulation Stress-induced blood-brain barrier damage

Kwon, Sung Chul
IRNA biology and genome engineering

Lee, Chi Wai
Intracellular trafficking of proteins and organelles Cytoskeletal dynamics in neuronal motility Pathogenesis of muscular dystrophy

Lim, Lee Wei
Deep brain stimulation in neurological and neuropsychiatric diseases Behavioral, cellular and molecular neurosciences

Ling, Guang Sheng Heidi
Metabolic reprogramming of CD8⁺T cells in chronic inflammatory diseases

Liu, Yang
How epigenetic markers on chromatin are regulated by histone chaperones and chromatin remodelers

Ni, Tao
Host – pathogen interaction Pore-forming proteins Macromolecule assembly mechanism Cryo-electron tomography and subtomogram averaging

Shih, David Jen Hao
Cancer genomics and somatic evolution Bayesian statistical modeling of complex biological data Deep learning for computational biology and medicine

Sugimura, Rio Ryohichi
Innate Immunity Cancer Immunotherapy Organoids & Stem Cells

Ti, Shih Chieh Jeff
The regulation of microtubule cytoskeleton

Yu, Cheng-Han
Integrin signaling in cell-matrix adhesion Lipid signaling in podosomes and invadopodia Mechanobiology and cancer metastasis Advanced fluorescence microscopy and image analysis Bio-functionalized supported lipid membrane

Zhou, Keda
Chromatin higher order structures Factors modulating chromatin structures during transcription Structure and dynamics of large molecular machines in DNA related processes

Chan, Vera Sau Fong (joint appointment with Department of Medicine)
Innate receptors immunobiology: C-type lectin receptors and Toll-like receptors and their roles in autoimmune diseases and infection Cellular immuno-dysregulation in systemic lupus erythematosus Molecular profiling and biomarkers development for SLE Molecular and cellular immunology; animal models for autoimmune diseases

Chu, Zhiqin (joint appointment with Department of Electrical and Electronic Engineering)
Precision biosensing/imaging (e.g., Spin defects in diamond for bio-oriented quantum sensing) Biophysics Biophotonics and materials-biology interface

Chung, Yik Sham Clive (joint appointment with Department of Pathology)
Chemical biology Organic synthesis of novel functional tools and drug lead compounds for biological studies and diease therapy Chemoproteomics and mass spectrometry (MS) Molecular imaging of cellular signaling molecules

Huang, Yuanhua (joint appointment with Department of Statistics and Actuarial Science)
Bioinformatics Single-cell genomics RNA splicing Cancer evolution Statistical modelling Machine learning

Wong, Alan Siu Lun (joint appointment with Department of Electrical and Electronic Engineering)
Combinatorial genetics Genome engineering Protein engineering Synthetic biology Disease biology Combination therapy