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Principal Investigators


He, Mu  

  • Development and regeneration of the respiratory system 
  • Airway mucus and cilia interaction 
  • Airway organoid platforms for human disease modeling

Hervas Millan, Rubén

  • Biophysics and protein structure
  • Protein aggregation in physiological processes
  • Structure and activity of functional amyloids

Javed, Asif

  • Multi-omics analysis of cancers and rare diseases
  • Computational biology

Kim, Jung

  • Systemic tumor-host interactions
  • Paraneoplastic syndromes
  • Tumor-dependent stem cell dysregulation
  • Stress-induced blood-brain barrier damage

Kwon, Sung Chul

  • IRNA biology and genome engineering

Ling, Guang Sheng Heidi

  • Metabolic reprogramming of CD8T cells in chronic inflammatory diseases

Liu, Yang

  • How epigenetic markers on chromatin are regulated by histone chaperones and chromatin remodelers

Ni, Tao

  • Host – pathogen interaction
  • Pore-forming proteins
  • Macromolecule assembly mechanism
  • Cryo-electron tomography and subtomogram averaging

Shih, David Jen Hao

  • Cancer genomics and somatic evolution
  • Bayesian statistical modeling of complex biological data
  • Deep learning for computational biology and medicine

Sugimura, Rio Ryohichi

  • Innate Immunity
  • Cancer Immunotherapy
  • Organoids & Stem Cells

Ti, Shih Chieh Jeff

  • The regulation of microtubule cytoskeleton

Wang, Shoutang

  • Microglia and neurodegenerative diseases
  • Immunotherapy and translational medicine
  • Cell signaling

Zhou, Keda

  • Chromatin higher order structures
  • Factors modulating chromatin structures during transcription
  • Structure and dynamics of large molecular machines in DNA related processes

Chu, Zhiqin (Joint appointment with Department of Electrical and Electronic Engineering)

  • Precision biosensing/imaging (e.g., Spin defects in diamond for bio-oriented quantum sensing)
  • Biophysics
  • Biophotonics and materials-biology interface

Chung, Yik Sham Clive (Joint appointment with Department of Pathology)

  • Chemical biology
  • Organic synthesis of novel functional tools and drug lead compounds for biological studies and diease therapy
  • Chemoproteomics and mass spectrometry (MS)
  • Molecular imaging of cellular signaling molecules

Huang, Yuanhua (Joint appointment with Department of Statistics and Actuarial Science)

  • Bioinformatics
  • Single-cell genomics
  • RNA splicing
  • Cancer evolution
  • Statistical modelling
  • Machine learning