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Principal Investigators

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Chan, Danny

  • Role of cellular stress signals in the pathogenesis of osteochondrodysplasias
  • Extracellular matrix in stem cell maintenance and differentiation
  • Generation and analysis of mouse models with skeletal abnormal abnormalities or intervertebral disc degeneration
  • Molecular mechanisms for skeletal patterning: Joint formation and digit patterning

Chan, Ying Shing

  • Neural plasticity: Circuitry development & rewiring after injury

Cheah, Kathryn Song Eng

  • Genotype – phenotype relationships
  • The genetic and molecular basis of inherited and degenerative skeletal disorders
  • Bioinformatic approaches for the identification of regulatory sequences in the genome
  • Understanding genes, their regulation and function with emphasis on development
  • The identification of genetic modifiers of congenital heart malformations

Hao, Quan

  • Structural biology
  • Synchrotron radiation

Huang, Jiandong

  • Recombineering
  • Intracellular transportation
  • Synthetic biology

Huen, Michael Shing Yan

  • DNA Damage Detection and Repair Control

Jin, Dong-Yan

  • Molecular virology and oncology

Liu, Pengtao

  • Establishment, characterization and application of totipotent and pluripotent stem cells
  • Hematopoiesis and immune cell functions
  • Cancer cell killers and immunotherapies

Tanner, Julian Alexander

  • Chemical Biology
  • Directed Nucleic Acid Evolution for Biomedical Application
  • Inorganic Polyphosphate Function

Zhou, Zhongjun

  • Aging, Chromatin Dynamics and Genomic maintenance
  • Stem cell self-renewal and differentiation in development, aging and cancer
  • Extracellular matrix and cell surface proteinases in regulation of growth factor signalling in development and diseases