CANCELLED

Dr. Juan Li
Senior Research Associate
Wellcome & MRC Cambridge Stem Cell Institute, UK

Date: Monday, 19-August-2019
Time: 11:00 a.m.
Venue: Seminar Room 1A & 1B, G/F, Jockey Club Building for Interdisciplinary Research
5 Sassoon Road, Pokfulam, Hong Kong

Summary:
Myeloproliferative neoplasms (MPNs) arise from the transformation of haematopeiotic stem cells and are associated with overproduction of specific lineages. Their study is providing powerful insights into the earliest stages of tumorigenesis and has broad relevance for cancer and stem cell biology. The BCR-ABL negative MPNs represent a spectrum of clonal disorders, with three main members: polycythaemia vera (PV), essential thrombocythaemia (ET) and primary myelofibrosis (PMF). The talk will highlight Dr. Li’s group’s studies on how JAK2V617F and CALRdel mutations drive the development of MPN-like diseases in murine models. 

ALL ARE WELCOME