Dr. Ludmila Prokunina-Olsson

Senior Investigator, Laboratory of Translational Genomics
Division of Cancer Epidemiology and Genetics
National Cancer Institute, National Institutes of Health, USA

Date: Mon, 12-June-2017
Time: 11:00 AM
Venue: Room A2-08, Mrs Chen Yang Foo Oi Telemedicine Centre 
2/F, William MW Mong Block, Faculty of Medicine Building 
21 Sassoon Road, Pokfulam, Hong Kong

Summary:

Germline genetic variants regulating expression and activity of APOBEC3 enzymes and IFN-λ4, a novel type-III interferon, significantly affect immune response to viral infections, and are associated with cancer risk and clinical outcomes. Population-specific distribution of these variants provides evidence of past or ongoing selection, which is suggestive of their importance in different infectious environments. Understanding the molecular mechanisms of these associations is important for improving viral clearance and developing novel cancer prevention and treatment strategies.

Organized by:

• Strategic Research Theme of Cancer
• Area of Excellence Scheme - Center for Nasopharyngeal Carcinoma Research
• School of Biomedical Sciences

ALL ARE WELCOME