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Jan 18, 2017

Seminar - Protein-protein interaction network in DNA damage response and tumorigenesis (Speaker: Professor Junjie Chen)

Professor Junjie Chen
Professor and Chair 
Department of Experimental Radiation Oncology 
Division of Radiation Oncology 
The University of Texas Anderson Cancer Center 
Houston, Texas, USA

Date: Wednesday, 18-January-2017
Time: 4:00 p.m.
Venue: Seminar Room 3, 
G/F, Jockey Club Building for Interdisciplinary Research
5 Sassoon Road, Pokfulam, Hong Kong​


Dr. Chen's lab focuses on elucidating the molecular mechanisms underlying genomic instability and tumorigenesis. The maintenance of genomic integrity following DNA damage depends on the coordination of DNA repair with cell cycle checkpoint control, which is crucial for tumor suppression. Using cell biology, genetics, and advanced proteomics approaches, Dr. Chen's group discovered and studied many new components and protein-protein interactions involved in DNA damage response. Collectively, these studies revealed mechanistically how cells promote cell survival and genome stability in response to exogenous and endogenous DNA lesions.