Dr Kenth Gustafsson​
Reader, Molecular Immunology Unit
University College London Institute of Child Health London
United Kingdom

Date: Thursday, 15-March-2018
Time: 4:00 p.m.
Venue: Seminar Room 4, G/F, Laboratory Block,
Faculty of Medicine Building,
21 Sassoon Road, Pokfulam, Hong Kong

Summary:
γ/δ T-cells form a unique niche at the interface of innate and adaptive immunity. They act as early cellular stress sensors and can innately kill transformed and infected cells, as well as free bacteria. Remarkably, after their cytotoxic activity, accompanied by inflammatory cytokine production, they are able to change phenotype and function into efficient professional phagocytosing and MHC peptide presenting cells. This behaviour, in combination with the ease by which they can be expanded in large numbers ex vivo, offers exciting opportunities in the fields of cancer immunotherapy as well as in the development of novel antimicrobial strategies.

ALL ARE WELCOME