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Sep 06, 2017

Seminar - Regulation and application of pluripotent stem cell-derived cardiac lineage cells (Speaker: Professor Huang-Tian Yang)

Professor Huang-Tian Yang
Chief of Laboratory of Molecular Cardiology
Shanghai Institutes for Biological Sciences
Chinese Academy of Sciences

Date: Wed, 6-September-2017
Time: 3:00 PM
Venue: Seminar Room 4, G/F, Laboratory Block,
Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong

Progenitor/stem cells and derivatives from pluripotent stem cells (hPSCs) hold a great promise for a new era of cell-based therapy in salvaging the failing heart, however, how the PSCs differentiate into cardiac lineage cells has not yet been fully understood and the optimal cell type for regeneration of the failing heart is still under the investigation. In the past, we investigated the role of Ca2+ signals and small molecular compounds in the regulation of cardiogenesis and developed a chemically defined system for the robust induction of cardiovascular progenitor cells (CVPCs) from pluripotent stem cells (hPSCs). Currently, we are testing the therapeutic effects of hPSC-derived cardiac lineage cells in the myocardial infarct model of adult mouse and elucidating potential mechanisms for cardiac repair. 

Organized by:

  • Li Ka Shing Faculty of Medicine
  • School of Biomedical Sciences
  • Stem Cell and Regenerative Medicine Consortium