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May 22, 2019

Seminar - Shining light at development (Speaker: Dr. Irina V. Larina)

Dr. Irina V. Larina
Associate Professor
Co-Director, Optical Imaging and Vital Microscopy Core
Molecular Physiology & Biophysics
Baylor College of Medicine, Houston, USA

Date: Wednesday, 22-May-2019
Time: 4:00 p.m.
Venue: Seminar Room 3, G/F, Laboratory Block
Faculty of Medicine Building
21 Sassoon Road, Pokfulam, Hong Kong

Early mammalian development is accompanied by very dynamic and dramatic structural changes on different spatial scales, which are hidden from live observation by layers of dense maternal tissue. To investigate developmental dynamics in its native state, Dr. Larina’s group developed a series of imaging methods combining functional optical coherence tomography (OCT), optogenetic control, non-linear microscopy, intravital imaging approaches and mouse models of human developmental defects. These methods uncover never-before-seen dynamic events, which suggest novel roles of biomechanics in embryonic development, and open doors for variety of studies on investigation of developmental mechanisms and embryonic failures.