Seminars
Jul 30, 2026
Regulation of the host immune response to infection by the cytoskeleton network
Speaker: Dr. Yaming Jiu
Principal investigator, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
School of Biomedical Sciences cordially invites you to join the following seminar:
Date: 30 July 2026 (Thursday)
Time: 10:00 am – 11:00 am
Venue: Seminar Room 1, G/F, Laboratory Block, 21 Sassoon Road
Host: Professor Jeff Ti
Biography
Dr. Yaming Jiu is a Principal investigator in Chinese Academy of Sciences. Her research focuses on using advanced imaging technologies to study the dynamic assembly mechanisms of the cytoskeleton and its pathological roles in cancer and pathogen infection. She has led several key projects, including the Key Program of National Natural Science Foundation of China, the National Excellent Youth Science Fund, and the CAS Pioneer Action Program. Dr. Jiu serves as an Associate Editor for the European Journal of Cell Biology and is on the Young Advisory Board of the Journal of Cell Biology. She has published over 70 SCI research papers, with more than 40 as a corresponding author in journals such as Developmental Cell, The EMBO Journal, Nature Communications, PNAS, Journal of Cell Biology, and Current Biology.
Abstract
The cytoskeleton network plays a critical role in both cellular structure (fine and dynamic) and functions such as signal transduction, infection immunity, transcription, and translation. It often operates in coordination with other subcellular organelles and external stimuli. Cell motility depends on the assembly of actin filaments and their interaction with intermediate filaments (e.g., in cancer cell metastasis). Cell division relies on microtubule-mediated segregation of genetic material and actin filament-dependent cytoplasmic reorganization (e.g., in the proliferation of cancer cells). Cellular mechanosensing depends on the balanced maintenance of actin filament-based stress fibers and the resilience of intermediate filaments (e.g., in the physicochemical microenvironment of cells). The maintenance of cellular integrity and stress responses, particularly under pathogenic infection, depends on the dynamic reorganization of intermediate filaments. Focusing on the cytoskeleton as a primary research subject, we aim to comprehensively understand cellular biological processes under tumorigenic and infectious conditions across scales—from molecules and subcellular organelles to cells and living organisms—and strive to identify novel drug targets and therapeutic strategies for the precision treatment of related diseases.
All are welcome.
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