Knowledge Exchange
Media Coverage: Article series for am730 health column
Oct 11, 2023
Article series are published for am730 health column to deliver public education on health-related issues.
Press Release: HKUMed & CityU researchers jointly generate human neural stem cells with powerful therapeutic potential for the treatment of spinal cord injury, paving the way for new therapeutic opportunities
Aug 16, 2023
A joint research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) and City University of Hong Kong (CityU) has generated human neural stem cells with powerful therapeutic potential for the treatment of spinal cord injury that paves the way for new therapeutic opportunities. The new findings are now published in Advanced Science.
Media Coverage: Dr Raymond Chang hosted a summer internship programme to study pathological changes and neural circuits of zebrafish
Jul 31, 2023
Dr Raymond Chang hosted a summer internship programme to study pathological changes and neural circuits of zebrafish.
Press Release: HKUMed discovers a novel molecular mechanism driving chemoresistance and tumour recurrence in gastric cancer, unveiling an actionable target for the disease
Jul 18, 2023
A research team led by Professor Stephanie Ma has uncovered a novel signaling pathway by which RNA editing governs lipid metabolism to promote resistance to chemotherapy and cancer stemness in gastric cancer. The findings has been published in Nature Communications.
Press Release: HKUMed in collaboration with the Hong Kong Sanatorium & Hospital, establishes the positive clinical impact of the Multidisciplinary Molecular Tumour Board among patients with advanced solid cancer in the era of Precision Cancer Medicine
Jul 03, 2023
Dr Jason Wong of the School and members of the collaborative group have recently published findings on the clinical importance of the Multidisciplinary Molecular Tumour Board (MTB) in delivering a Precision Cancer Medicine service.
Press Release: HKUMed establishes the first platform to slash time engineering and selecting the best precise genome editors for applications
Jun 19, 2023
A research team from the HKUMed has developed a new way to breakthrough the current limited throughput in optimising precise genome editors at scale, engineer hundreds (or more) of base editor variants in parallel instead of current laborious one-by-one testing, and informing users of the most suitable ones for therapeutic genome editing. The finding has been published in Cell Systems and a patent application has been filed based on this work.
Press Release: HKUMed discovers a new tumour suppressive gene which boosts personalised treatment response in breast cancer
Feb 02, 2023
A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumour suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy. The findings are now published in Cell Reports
Press Release: HKUMed uncovers an unexpected T cell exhaustion factor driving cancer immunotherapy resistance
Jan 26, 2023
A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has identified an unexpected driver of cancer immunotherapy resistance: the harmful effect of chronic Type I Interferon signalling on tumour-killing CD8+ T cells. These findings provided new insights into the development of exhausted CD8+ T cells, which no longer effectively limit tumour growth, and highlighted a new target for immunotherapy improvement. The research has been published in Cell Reports
Media Coverage: Dr Stephanie Ma shared her thoughts after being awarded Croucher Senior Research Fellowship 2023
Dec 28, 2022
Dr Stephanie Ma shared her thoughts after being awarded Croucher Senior Research Fellowship 2023.
Press Release: HKUMed scientists lead discovery of two master genes critical for hearing, providing a guide for diagnosis of deafness and balance problems
Dec 05, 2022
An international team of scientists led by the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has uncovered the underlying cause of deafness caused by swelling of the chambers in the inner ear. Using a mouse model of a human congenital disorder that displays deafness, the researchers identified two master genes controlling hearing function, which opened a new pathway for diagnosis of deafness and balance problems, and possibly to the effects on stem cells in other tissues and syndromes. This exciting advance is described in their paper published in the premier life sciences journal, Proceedings of the National Academy of Sciences.