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Press Release: HKUMed discovers a novel molecular mechanism driving chemoresistance and tumour recurrence in gastric cancer, unveiling an actionable target for the disease

Press Release: HKUMed discovers a novel molecular mechanism driving chemoresistance and tumour recurrence in gastric cancer, unveiling an actionable target for the disease

A research team led by Professor Stephanie Ma has uncovered a novel signaling pathway by which RNA editing governs lipid metabolism to promote resistance to chemotherapy and cancer stemness in gastric cancer. The findings has been published in Nature Communications.

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Press Release: HKUMed in collaboration with the Hong Kong Sanatorium & Hospital, establishes the positive clinical impact of the Multidisciplinary Molecular Tumour Board among patients with advanced solid cancer in the era of Precision Cancer Medicine

Press Release: HKUMed in collaboration with the Hong Kong Sanatorium & Hospital, establishes the positive clinical impact of the Multidisciplinary Molecular Tumour Board among patients with advanced solid cancer in the era of Precision Cancer Medicine

Dr Jason Wong of the School and members of the collaborative group have recently published findings on the clinical importance of the Multidisciplinary Molecular Tumour Board (MTB) in delivering a Precision Cancer Medicine service.

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Press Release: HKUMed establishes the first platform to slash time engineering and selecting the best precise genome editors for applications

Press Release: HKUMed establishes the first platform to slash time engineering and selecting the best precise genome editors for applications

A research team from the HKUMed has developed a new way to breakthrough the current limited throughput in optimising precise genome editors at scale, engineer hundreds (or more) of base editor variants in parallel instead of current laborious one-by-one testing, and informing users of the most suitable ones for therapeutic genome editing. The finding has been published in Cell Systems and a patent application has been filed based on this work.

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Press Release: HKUMed discovers a new tumour suppressive gene which boosts personalised treatment response in breast cancer

Press Release: HKUMed discovers a new tumour suppressive gene which boosts personalised treatment response in breast cancer

A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumour suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy. The findings are now published in Cell Reports

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Press Release: HKUMed uncovers an unexpected T cell exhaustion factor driving cancer immunotherapy resistance

Press Release: HKUMed uncovers an unexpected T cell exhaustion factor driving cancer immunotherapy resistance

A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has identified an unexpected driver of cancer immunotherapy resistance: the harmful effect of chronic Type I Interferon signalling on tumour-killing CD8+ T cells. These findings provided new insights into the development of exhausted CD8+ T cells, which no longer effectively limit tumour growth, and highlighted a new target for immunotherapy improvement. The research has been published in Cell Reports

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Media Coverage: Dr Stephanie Ma shared her thoughts after being awarded Croucher Senior Research Fellowship 2023

Media Coverage: Dr Stephanie Ma shared her thoughts after being awarded Croucher Senior Research Fellowship 2023

Dr Stephanie Ma shared her thoughts after being awarded Croucher Senior Research Fellowship 2023.

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Press Release: HKUMed scientists lead discovery of two master genes critical for hearing, providing a guide for diagnosis of deafness and balance problems

Press Release: HKUMed scientists lead discovery of two master genes critical for hearing, providing a guide for diagnosis of deafness and balance problems

An international team of scientists led by the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has uncovered the underlying cause of deafness caused by swelling of the chambers in the inner ear. Using a mouse model of a human congenital disorder that displays deafness, the researchers identified two master genes controlling hearing function, which opened a new pathway for diagnosis of deafness and balance problems, and possibly to the effects on stem cells in other tissues and syndromes. This exciting advance is described in their paper published in the premier life sciences journal, Proceedings of the National Academy of Sciences.

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Press Release: Professor Ying Shing Chan, Dr Lee Wei Lim and CityU researchers jointly discover non-invasive stimulation of the eye for depression and dementia

Press Release: Professor Ying Shing Chan, Dr Lee Wei Lim and CityU researchers jointly discover non-invasive stimulation of the eye for depression and dementia

A joint research team of Professor Ying Shing Chan, Dr Lee Wei Lim and City University of Hong Kong (CityU) has discovered that the electrical stimulation of the eye surface can alleviate depression-like symptoms and improve cognitive function in animal models. These significant findings were recently published in Brain Stimulation and the Annals of the New York Academy of Sciences.

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Press Release: Dr Alan Wong and his team combine artificial intelligence and protein engineering technology to enhance gene editing efficiency of CRISPR-Cas9

Press Release: Dr Alan Wong and his team combine artificial intelligence and protein engineering technology to enhance gene editing efficiency of CRISPR-Cas9

Dr Alan Wong and his team discovered more efficient CRISPR-Cas9 variants that could be useful for gene therapy applications. The findings are now published in Nature Communications (link to the publication) and a patent application has been filed based on this work.

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Media Coverage: BBMS Graduate being interviewed by local media to share his experience in enrolling the BBiomedSc Articulation Programme

Media Coverage: BBMS Graduate being interviewed by local media to share his experience in enrolling the BBiomedSc Articulation Programme

Media Coverage: BBMS Graduate being interviewed by local media to share his experience in enrolling the BBiomedSc Articulation Programme

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